| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | PRIMECAP Management Company | 8.27M (17.78%) | -31.90K Decreased by -0.39% | Sep 30, 23 |
| 2 | Baker Bros Advisors LP | 6.70M (14.41%) | 204.08K Increased by +3.04% | Sep 30, 23 |
| 3 | BlackRock Inc | 6.20M (13.33%) | -65.12K Decreased by -1.05% | Sep 30, 23 |
| 4 | RA Capital Management, LLC | 5.68M (12.20%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 5 | Goldman Sachs Group Inc | 5.16M (11.10%) | -25.47K Decreased by -0.49% | Sep 30, 23 |
| 6 | Vanguard Group Inc | 3.01M (6.48%) | 85.14K Increased by +2.82% | Sep 30, 23 |
| 7 | NEA Management Company, LLC | 2.91M (6.26%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 8 | Polar Capital Holdings PLC | 2.50M (5.38%) | 250.00K Increased by +10.00% | Sep 30, 23 |
| 9 | State Street Corporation | 2.37M (5.09%) | -901.57K Decreased by -38.11% | Sep 30, 23 |
| 10 | Federated Hermes Inc | 2.34M (5.03%) | -1.55M Decreased by -66.22% | Sep 30, 23 |
| 11 | COMMODORE CAPITAL LP | 2.08M (4.46%) | 2.08M Increased by +100.00% | Sep 30, 23 |
| 12 | Alkeon Capital Management, LLC | 1.73M (3.71%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | Rock Springs Capital Management LP | 1.60M (3.43%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | VR Adviser, LLC | 1.09M (2.34%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | HHG PLC | 1.07M (2.29%) | -12.46K Decreased by -1.17% | Sep 30, 23 |
| 16 | Geode Capital Management, LLC | 1.05M (2.25%) | 71.71K Increased by +6.86% | Sep 30, 23 |
| 17 | FMR Inc | 868.47K (1.87%) | 166.94K Increased by +19.22% | Sep 30, 23 |
| 18 | Cormorant Asset Management, LLC | 850.00K (1.83%) | 250.00K Increased by +29.41% | Sep 30, 23 |
| 19 | Opaleye Management Inc | 653.00K (1.40%) | -82.00K Decreased by -12.56% | Sep 30, 23 |
| 20 | Orbimed Advisors, LLC | 583.64K (1.25%) | 583.64K Increased by +100.00% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | PRIMECAP Odyssey Aggressive Growth | 5.36M (11.53%) | -32.10K Decreased by -0.60% | Sep 30, 23 |
| 2 | PRIMECAP Odyssey Growth | 2.55M (5.48%) | 204.00 Increased by +0.01% | Sep 30, 23 |
| 3 | Polar Capital Biotech S Inc | 2.00M (4.30%) | -428.03K Decreased by -21.40% | Nov 30, 23 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 1.79M (3.84%) | 3.16K Increased by +0.18% | Nov 30, 23 |
| 5 | iShares Russell 2000 ETF | 1.37M (2.96%) | 8.73K Increased by +0.64% | Dec 29, 23 |
| 6 | Federated Hermes Kaufmann Growth | 1.23M (2.63%) | -994.98K Decreased by -81.22% | Sep 30, 23 |
| 7 | Federated Hermes Kaufmann R | 1.23M (2.63%) | -994.98K Decreased by -81.22% | Sep 30, 23 |
| 8 | Federated Hermes Kaufmann Small Cap A | 1.08M (2.33%) | -523.86K Decreased by -48.28% | Sep 30, 23 |
| 9 | Federated Hermes Kaufmann Small Cap Grow | 1.08M (2.33%) | -523.86K Decreased by -48.28% | Sep 30, 23 |
| 10 | SPDR® S&P Biotech ETF | 1.08M (2.32%) | -6.25K Decreased by -0.58% | Dec 31, 23 |
| 11 | UBS: US Equity Small Cap Growth | 795.76K (1.71%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 12 | Fidelity® Select Biotechnology | 786.90K (1.69%) | -75.80K Decreased by -9.63% | Nov 30, 23 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 706.97K (1.52%) | 1.22K Increased by +0.17% | Nov 30, 23 |
| 14 | BlackRock Health Sciences Opps Inv A | 690.35K (1.48%) | -66.50K Decreased by -9.63% | Nov 30, 23 |
| 15 | BGF World Healthscience A2 | 660.37K (1.42%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 16 | BlackRock Health Sciences Term Trust | 584.77K (1.26%) | -98.90K Decreased by -16.91% | Nov 30, 23 |
| 17 | Janus Henderson Global Life Sciences | 500.00K (1.08%) | -2.06K Decreased by -0.41% | Sep 30, 23 |
| 18 | Janus Henderson Global Life Sciences D | 500.00K (1.08%) | -2.06K Decreased by -0.41% | Sep 30, 23 |
| 19 | Fidelity® Small Cap Index | 496.21K (1.07%) | 13.46K Increased by +2.71% | Oct 31, 23 |
| 20 | iShares Russell 2000 Growth ETF | 457.06K (0.98%) | 0.00 Increased by 0.00% | Dec 29, 23 |