| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bvf Inc | 5.74M (15.50%) | 1.97M Increased by +34.27% | Sep 30, 23 |
| 2 | Farallon Capital Management, L.L.C. | 5.45M (14.70%) | 935.00K Increased by +17.17% | Sep 30, 23 |
| 3 | RTW INVESTMENTS, LLC | 5.42M (14.62%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 4 | BlackRock Inc | 5.23M (14.11%) | 220.15K Increased by +4.21% | Sep 30, 23 |
| 5 | State Street Corporation | 3.94M (10.64%) | 390.15K Increased by +9.90% | Sep 30, 23 |
| 6 | Vanguard Group Inc | 3.23M (8.71%) | 80.64K Increased by +2.50% | Sep 30, 23 |
| 7 | Johnson & Johnson | 2.45M (6.61%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 8 | Kynam Capital Management, LP | 1.82M (4.91%) | 843.36K Increased by +46.37% | Sep 30, 23 |
| 9 | COWEN AND COMPANY, LLC | 1.66M (4.47%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 10 | Geode Capital Management, LLC | 1.18M (3.19%) | 104.07K Increased by +8.81% | Sep 30, 23 |
| 11 | BRAIDWELL LP | 1.11M (2.99%) | 1.11M Increased by +100.00% | Sep 30, 23 |
| 12 | Point72 Asset Management, L.P. | 1.11M (2.99%) | 1.11M Increased by +100.00% | Sep 30, 23 |
| 13 | Perceptive Advisors LLC | 1.05M (2.85%) | -415.49K Decreased by -39.41% | Sep 30, 23 |
| 14 | Dimensional Fund Advisors, Inc. | 941.27K (2.54%) | -97.83K Decreased by -10.39% | Sep 30, 23 |
| 15 | Jefferies Financial Group Inc | 835.56K (2.26%) | 75.00K Increased by +8.98% | Sep 30, 23 |
| 16 | T. Rowe Price Associates, Inc. | 831.99K (2.25%) | 300.00 Increased by +0.04% | Sep 30, 23 |
| 17 | 683 Capital Management LLC | 732.78K (1.98%) | -81.22K Decreased by -11.08% | Sep 30, 23 |
| 18 | Adage Capital Partners Gp LLC | 700.00K (1.89%) | -592.71K Decreased by -84.67% | Sep 30, 23 |
| 19 | Candriam Luxembourg S.C.A. | 630.00K (1.70%) | -95.00K Decreased by -15.08% | Sep 30, 23 |
| 20 | Northern Trust Corp | 562.69K (1.52%) | 24.56K Increased by +4.37% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.70M (4.59%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 2 | iShares Russell 2000 ETF | 1.53M (4.14%) | 9.76K Increased by +0.64% | Dec 29, 23 |
| 3 | SPDR® S&P Biotech ETF | 1.49M (4.02%) | -8.62K Decreased by -0.58% | Dec 31, 23 |
| 4 | Vanguard Institutional Extnd Mkt Idx Tr | 817.30K (2.21%) | 21.00K Increased by +2.57% | Nov 30, 23 |
| 5 | Candriam Eqs L Biotech C USD Cap | 630.00K (1.70%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 6 | Fidelity® Small Cap Index | 550.28K (1.49%) | 14.68K Increased by +2.67% | Oct 31, 23 |
| 7 | Fidelity® Select Biotechnology | 422.31K (1.14%) | -36.90K Decreased by -8.74% | Nov 30, 23 |
| 8 | BlackRock Health Sciences Term Trust | 421.73K (1.14%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 9 | iShares Biotechnology ETF | 404.05K (1.09%) | -368.00 Decreased by -0.09% | Dec 29, 23 |
| 10 | BlackRock Health Sciences Opps Inv A | 403.94K (1.09%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 11 | Direxion Daily S&P Biotech Bull 3X ETF | 341.54K (0.92%) | 7.64K Increased by +2.24% | Nov 30, 23 |
| 12 | State St Russell Sm/Mid Cp® Indx NL Cl C | 336.19K (0.91%) | 14.10K Increased by +4.19% | Dec 31, 23 |
| 13 | Eventide Healthcare & Life Sciences I | 320.00K (0.86%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | iShares Russell 2000 Growth ETF | 318.18K (0.86%) | 0.00 Increased by 0.00% | Dec 29, 23 |
| 15 | Fidelity® Extended Market Index | 310.21K (0.84%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 16 | Schwab US Small-Cap ETF™ | 260.86K (0.70%) | 114.00 Increased by +0.04% | Dec 30, 23 |
| 17 | DFA US Micro Cap I | 244.02K (0.66%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 18 | State St Russell Sm Cap® Indx SL Cl I | 215.18K (0.58%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 19 | DFA US Small Cap I | 213.13K (0.58%) | -25.40K Decreased by -11.92% | Nov 30, 23 |
| 20 | TIAA-CREF Quant Small-Cap Equity Instl | 209.69K (0.57%) | 0.00 Increased by 0.00% | Nov 30, 23 |