| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | COMMODORE CAPITAL LP | 4.43M (10.58%) | 428.07K Increased by +9.67% | Sep 30, 23 |
| 2 | Deerfield Management Co | 3.88M (9.26%) | 845.00K Increased by +21.80% | Sep 30, 23 |
| 3 | Samlyn Capital, LLC | 3.26M (7.78%) | 419.07K Increased by +12.87% | Sep 30, 23 |
| 4 | Federated Hermes Inc | 2.89M (6.90%) | 247.00K Increased by +8.56% | Sep 30, 23 |
| 5 | Bvf Inc | 2.75M (6.58%) | 1.15M Increased by +41.78% | Sep 30, 23 |
| 6 | Wellington Management Company LLP | 2.74M (6.54%) | 60.13K Increased by +2.20% | Sep 30, 23 |
| 7 | RTW INVESTMENTS, LLC | 2.00M (4.77%) | 945.87K Increased by +47.37% | Sep 30, 23 |
| 8 | BRAIDWELL LP | 1.90M (4.54%) | 358.18K Increased by +18.84% | Sep 30, 23 |
| 9 | Boxer Capital LLC | 1.90M (4.54%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 10 | Franklin Resources Inc | 1.89M (4.52%) | 299.67K Increased by +15.84% | Sep 30, 23 |
| 11 | Fairmount Funds Management LLC | 1.88M (4.50%) | 398.94K Increased by +21.21% | Sep 30, 23 |
| 12 | VR Adviser, LLC | 1.73M (4.12%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | Medicxi Ventures Management (Jersey) Ltd | 1.60M (3.82%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | BlackRock Inc | 1.47M (3.50%) | 280.12K Increased by +19.11% | Sep 30, 23 |
| 15 | Driehaus Capital Management LLC | 1.14M (2.71%) | -1.52K Decreased by -0.13% | Sep 30, 23 |
| 16 | Balyasny Asset Management LLC | 860.36K (2.06%) | 860.36K Increased by +100.00% | Sep 30, 23 |
| 17 | Rock Springs Capital Management LP | 838.43K (2.00%) | 359.90K Increased by +42.93% | Sep 30, 23 |
| 18 | FMR Inc | 774.95K (1.85%) | 180.40K Increased by +23.28% | Sep 30, 23 |
| 19 | Millennium Management LLC | 629.20K (1.50%) | 604.89K Increased by +96.14% | Sep 30, 23 |
| 20 | SILVERARC CAPITAL MANAGEMENT, LLC | 500.00K (1.19%) | -89.25K Decreased by -17.85% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Federated Hermes Kaufmann Small Cap A | 1.91M (4.55%) | 91.00K Increased by +4.77% | Sep 30, 23 |
| 2 | Federated Hermes Kaufmann Small Cap Grow | 1.91M (4.55%) | 91.00K Increased by +4.77% | Sep 30, 23 |
| 3 | Franklin Biotechnology Discv A(acc)USD | 1.05M (2.51%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 4 | Federated Hermes Kaufmann Growth | 955.00K (2.28%) | 155.00K Increased by +16.23% | Sep 30, 23 |
| 5 | Federated Hermes Kaufmann R | 955.00K (2.28%) | 155.00K Increased by +16.23% | Sep 30, 23 |
| 6 | Candriam Global Equities Oncology | 863.08K (2.06%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 7 | Belfius Equities Cure C Cap | 748.08K (1.79%) | -115.00K Decreased by -15.37% | Nov 30, 23 |
| 8 | Fidelity® Select Biotechnology | 730.45K (1.75%) | -63.80K Decreased by -8.73% | Nov 30, 23 |
| 9 | HBM Healthcare Investments AG Ord | 680.00K (1.62%) | -141.66K Decreased by -20.83% | Sep 30, 23 |
| 10 | Wellington Global Hlthcr Eq USD G Ac | 521.24K (1.25%) | -3.79K Decreased by -0.73% | Nov 30, 23 |
| 11 | Franklin Biotechnology Discovery A | 482.73K (1.15%) | -16.70K Decreased by -3.46% | Nov 30, 23 |
| 12 | Polar Capital Biotech S Inc | 425.00K (1.02%) | -75.00K Decreased by -17.65% | Nov 30, 23 |
| 13 | BlackRock Health Sciences Term Trust | 411.97K (0.98%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 14 | Candriam Eqs L Biotech C USD Cap | 400.15K (0.96%) | -98.00K Decreased by -24.49% | Nov 30, 23 |
| 15 | BlackRock Health Sciences Opps Inv A | 338.56K (0.81%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 16 | iShares Biotechnology ETF | 317.96K (0.76%) | -290.00 Decreased by -0.09% | Dec 29, 23 |
| 17 | Franklin Small Cap Growth Adv | 312.80K (0.75%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 18 | Franklin US Small Cap Growth Equity | 312.80K (0.75%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 19 | Carmignac Pf Grande Europe A EUR Acc | 300.85K (0.72%) | 20.33K Increased by +6.76% | Oct 31, 23 |
| 20 | Heptagon Driehaus US Micro Cap Eq C$ Acc | 272.88K (0.65%) | 4.54K Increased by +1.66% | Nov 30, 23 |