| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | EcoR1 Capital, LLC | 19.36M (24.26%) | 19.36M Increased by +100.00% | Sep 30, 23 |
| 2 | VR Adviser, LLC | 11.33M (14.19%) | 11.33M Increased by +100.00% | Sep 30, 23 |
| 3 | Bain Capital Life Sciences Investors, LLC | 8.66M (10.86%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 4 | BlackRock Inc | 7.97M (9.99%) | 8.68K Increased by +0.11% | Sep 30, 23 |
| 5 | Vanguard Group Inc | 6.19M (7.75%) | 461.50K Increased by +7.46% | Sep 30, 23 |
| 6 | Bellevue Group AG | 5.22M (6.54%) | -800.00 Decreased by -0.02% | Sep 30, 23 |
| 7 | Balyasny Asset Management LLC | 5.04M (6.32%) | 201.38K Increased by +4.00% | Sep 30, 23 |
| 8 | SILVERARC CAPITAL MANAGEMENT, LLC | 5.00M (6.26%) | 4.00M Increased by +80.00% | Sep 30, 23 |
| 9 | Rock Springs Capital Management LP | 3.40M (4.26%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 10 | Affinity Asset Advisors, LLC | 2.85M (3.57%) | 2.85M Increased by +100.00% | Sep 30, 23 |
| 11 | Philosophy Capital Management LLC | 2.34M (2.94%) | 2.34M Increased by +100.00% | Sep 30, 23 |
| 12 | State Street Corporation | 2.31M (2.90%) | -2.59M Decreased by -112.09% | Sep 30, 23 |
| 13 | COMMODORE CAPITAL LP | 2.24M (2.81%) | 2.24M Increased by +100.00% | Sep 30, 23 |
| 14 | Millennium Management LLC | 2.18M (2.73%) | 305.73K Increased by +14.04% | Sep 30, 23 |
| 15 | Geode Capital Management, LLC | 2.16M (2.70%) | 151.98K Increased by +7.04% | Sep 30, 23 |
| 16 | Walleye Trading Advisors, LLC | 2.02M (2.53%) | 1.87M Increased by +92.34% | Sep 30, 23 |
| 17 | Boxer Capital LLC | 2.00M (2.51%) | 1.00M Increased by +50.00% | Sep 30, 23 |
| 18 | Citadel Advisors Llc | 1.61M (2.02%) | 1.61M Increased by +100.00% | Sep 30, 23 |
| 19 | Ikarian Capital, LLC | 1.58M (1.98%) | 1.53M Increased by +96.83% | Sep 30, 23 |
| 20 | 5AM Venture Management, LLC | 1.30M (1.64%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 5.21M (6.52%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 3.41M (4.28%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 3 | iShares Russell 2000 ETF | 3.01M (3.77%) | 19.14K Increased by +0.64% | Dec 29, 23 |
| 4 | Vanguard Institutional Extnd Mkt Idx Tr | 1.50M (1.87%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 5 | Fidelity® Small Cap Index | 1.02M (1.27%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 6 | State St Russell Sm/Mid Cp® Indx NL Cl C | 648.77K (0.81%) | 96.00K Increased by +14.80% | Dec 31, 23 |
| 7 | iShares Biotechnology ETF | 639.36K (0.80%) | 2.36K Increased by +0.37% | Nov 30, 23 |
| 8 | iShares Russell 2000 Growth ETF | 617.67K (0.77%) | 0.00 Increased by 0.00% | Dec 29, 23 |
| 9 | Bridgeway Ultra-Small Company | 581.70K (0.73%) | 581.70K Increased by +100.00% | Sep 30, 23 |
| 10 | Fidelity® Extended Market Index | 508.16K (0.64%) | 83.33K Increased by +16.40% | Nov 30, 23 |
| 11 | Vanguard VIF Small Co Gr | 499.33K (0.63%) | 499.33K Increased by +100.00% | Sep 30, 23 |
| 12 | iShares Russell 2000 Value ETF | 427.50K (0.54%) | 795.00 Increased by +0.19% | Dec 29, 23 |
| 13 | Rhenman Healthcare Equity L/S RC2 SEK | 400.00K (0.50%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | State St Russell Sm Cap® Indx SL Cl I | 373.77K (0.47%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 15 | Vanguard Russell 2000 ETF | 321.47K (0.40%) | 3.03K Increased by +0.94% | Nov 30, 23 |
| 16 | NT R2000 Index Fund - NL | 287.61K (0.36%) | -581.00 Decreased by -0.20% | Sep 30, 23 |
| 17 | BlackRock Extended Mkt Composite | 250.23K (0.31%) | 1.90K Increased by +0.76% | Sep 30, 23 |
| 18 | Schwab Small Cap Index | 249.83K (0.31%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 19 | iShares Micro-Cap ETF | 244.59K (0.31%) | 0.00 Increased by 0.00% | Dec 29, 23 |
| 20 | Fidelity® Enhanced Small Cap ETF | 227.84K (0.29%) | 0.00 Increased by 0.00% | Nov 30, 23 |