| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 6.52M (16.86%) | -351.75K Decreased by -5.39% | Sep 30, 23 |
| 2 | Wellington Management Company LLP | 3.42M (8.85%) | 1.12M Increased by +32.67% | Sep 30, 23 |
| 3 | BlackRock Inc | 2.89M (7.47%) | 138.27K Increased by +4.79% | Sep 30, 23 |
| 4 | Point72 Asset Management, L.P. | 2.50M (6.48%) | 2.50M Increased by +100.00% | Sep 30, 23 |
| 5 | Artal Group S A | 2.14M (5.53%) | -1.81K Decreased by -0.08% | Sep 30, 23 |
| 6 | Vanguard Group Inc | 2.11M (5.45%) | 200.77K Increased by +9.53% | Sep 30, 23 |
| 7 | T. Rowe Price Associates, Inc. | 2.08M (5.38%) | -111.64K Decreased by -5.37% | Sep 30, 23 |
| 8 | State Street Corporation | 1.80M (4.65%) | 60.06K Increased by +3.34% | Sep 30, 23 |
| 9 | EcoR1 Capital, LLC | 1.48M (3.83%) | -2.37M Decreased by -159.90% | Sep 30, 23 |
| 10 | Woodline Partners LP | 1.22M (3.17%) | 730.45K Increased by +59.63% | Sep 30, 23 |
| 11 | Federated Hermes Inc | 884.02K (2.29%) | 12.90K Increased by +1.46% | Sep 30, 23 |
| 12 | Geode Capital Management, LLC | 777.17K (2.01%) | 115.03K Increased by +14.80% | Sep 30, 23 |
| 13 | T. Rowe Price Investment Management,Inc. | 629.78K (1.63%) | -141.25K Decreased by -22.43% | Sep 30, 23 |
| 14 | SILVERARC CAPITAL MANAGEMENT, LLC | 590.83K (1.53%) | 338.52K Increased by +57.30% | Sep 30, 23 |
| 15 | Dimensional Fund Advisors, Inc. | 529.81K (1.37%) | 38.18K Increased by +7.21% | Sep 30, 23 |
| 16 | Morgan Stanley - Brokerage Accounts | 528.44K (1.37%) | 265.63K Increased by +50.27% | Sep 30, 23 |
| 17 | Citadel Advisors Llc | 521.35K (1.35%) | 521.35K Increased by +100.00% | Sep 30, 23 |
| 18 | Deep Track Capital, LP | 470.65K (1.22%) | 253.90K Increased by +53.95% | Sep 30, 23 |
| 19 | Two Sigma Investments LLC | 414.24K (1.07%) | 400.14K Increased by +96.60% | Sep 30, 23 |
| 20 | Millennium Management LLC | 399.99K (1.03%) | 344.44K Increased by +86.11% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | SPDR® S&P Biotech ETF | 1.80M (4.65%) | -10.42K Decreased by -0.58% | Dec 31, 23 |
| 2 | Fidelity Growth Compy Commingled Pl O | 1.61M (4.17%) | 7.84K Increased by +0.49% | Nov 30, 23 |
| 3 | Fidelity® Growth Company | 1.31M (3.39%) | 36.90K Increased by +2.82% | Nov 30, 23 |
| 4 | Vanguard Health Care Inv | 1.24M (3.20%) | 621.11K Increased by +50.17% | Sep 30, 23 |
| 5 | Vanguard Total Stock Mkt Idx Inv | 1.17M (3.03%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 6 | Fidelity® Select Biotechnology | 1.12M (2.90%) | 264.96K Increased by +23.60% | Nov 30, 23 |
| 7 | iShares Russell 2000 ETF | 985.93K (2.55%) | 6.28K Increased by +0.64% | Dec 29, 23 |
| 8 | US Small-Cap Growth II Equity Comp | 936.24K (2.42%) | 936.24K Increased by +100.00% | Jun 30, 23 |
| 9 | T. Rowe Price New Horizons | 935.91K (2.42%) | -321.00 Decreased by -0.03% | Sep 30, 23 |
| 10 | Pictet-Biotech P USD | 591.92K (1.53%) | 58.46K Increased by +9.88% | Jun 30, 23 |
| 11 | Federated Hermes Kaufmann Small Cap A | 575.00K (1.49%) | 14.00K Increased by +2.43% | Sep 30, 23 |
| 12 | Federated Hermes Kaufmann Small Cap Grow | 575.00K (1.49%) | 14.00K Increased by +2.43% | Sep 30, 23 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 567.54K (1.47%) | 986.00 Increased by +0.17% | Nov 30, 23 |
| 14 | Vanguard Explorer Inv | 480.58K (1.24%) | 161.44K Increased by +33.59% | Sep 30, 23 |
| 15 | T. Rowe Price Health Sciences | 474.91K (1.23%) | -132.93K Decreased by -27.99% | Sep 30, 23 |
| 16 | Fidelity® Growth Company K6 | 411.67K (1.06%) | -44.74K Decreased by -10.87% | Nov 30, 23 |
| 17 | Fidelity Select Health Care | 400.00K (1.03%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 18 | Select Health Care | 400.00K (1.03%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 19 | Fidelity® Series Growth Company | 384.61K (0.99%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | Pictet-Global Megatrend Sel I USD | 361.88K (0.94%) | 24.90K Increased by +6.88% | Jun 30, 23 |