| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 3.04M (25.39%) | 1.56M Increased by +51.22% | Sep 30, 23 |
| 2 | Vanguard Group Inc | 1.57M (13.13%) | 107.82K Increased by +6.85% | Sep 30, 23 |
| 3 | venBio Select Advisor LLC | 1.55M (12.97%) | 39.85K Increased by +2.56% | Sep 30, 23 |
| 4 | Baker Bros Advisors LP | 1.55M (12.89%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 5 | BlackRock Inc | 1.03M (8.62%) | -10.81K Decreased by -1.05% | Sep 30, 23 |
| 6 | State Street Corporation | 642.27K (5.36%) | 98.51K Increased by +15.34% | Sep 30, 23 |
| 7 | Paulson & Company Inc | 500.00K (4.17%) | 149.80K Increased by +29.96% | Sep 30, 23 |
| 8 | FMR Inc | 440.38K (3.67%) | 91.34K Increased by +20.74% | Sep 30, 23 |
| 9 | Marshall Wace Asset Management Ltd | 395.40K (3.30%) | -65.25K Decreased by -16.50% | Sep 30, 23 |
| 10 | AllianceBernstein L.P. | 360.98K (3.01%) | -10.14K Decreased by -2.81% | Sep 30, 23 |
| 11 | RTW INVESTMENTS, LLC | 309.49K (2.58%) | 87.92K Increased by +28.41% | Sep 30, 23 |
| 12 | Geode Capital Management, LLC | 296.44K (2.47%) | 25.12K Increased by +8.47% | Sep 30, 23 |
| 13 | Artisan Partners Limited Partnership | 280.09K (2.34%) | 50.00K Increased by +17.85% | Sep 30, 23 |
| 14 | Citadel Advisors Llc | 276.83K (2.31%) | 192.92K Increased by +69.69% | Sep 30, 23 |
| 15 | Orbimed Advisors, LLC | 253.31K (2.11%) | -68.26K Decreased by -26.95% | Sep 30, 23 |
| 16 | RA Capital Management, LLC | 204.50K (1.71%) | 204.50K Increased by +100.00% | Sep 30, 23 |
| 17 | Rock Springs Capital Management LP | 196.37K (1.64%) | -2.85K Decreased by -1.45% | Sep 30, 23 |
| 18 | TCG Crossover Management, LLC | 179.92K (1.50%) | 30.00K Increased by +16.67% | Sep 30, 23 |
| 19 | Point72 Asset Management, L.P. | 172.90K (1.44%) | 172.90K Increased by +100.00% | Sep 30, 23 |
| 20 | Morgan Stanley - Brokerage Accounts | 171.77K (1.43%) | 97.48K Increased by +56.75% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Janus Concentrated Growth CF | 637.68K (5.32%) | 637.68K Increased by +100.00% | Sep 30, 23 |
| 2 | Janus Henderson Forty S | 637.68K (5.32%) | 637.68K Increased by +100.00% | Sep 30, 23 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 493.13K (4.11%) | 789.00 Increased by +0.16% | Nov 30, 23 |
| 4 | Janus Henderson Contrarian D | 415.98K (3.47%) | 91.04K Increased by +21.89% | Sep 30, 23 |
| 5 | Janus Henderson US Opportunistic Alpha | 415.98K (3.47%) | 91.04K Increased by +21.89% | Sep 30, 23 |
| 6 | Vanguard Small Cap Index | 408.55K (3.41%) | 1.25K Increased by +0.31% | Nov 30, 23 |
| 7 | iShares Russell 2000 ETF | 395.77K (3.30%) | 2.54K Increased by +0.64% | Dec 29, 23 |
| 8 | SPDR® S&P Biotech ETF | 382.30K (3.19%) | -2.21K Decreased by -0.58% | Dec 31, 23 |
| 9 | Janus Henderson Global Life Sciences | 348.34K (2.91%) | 111.97K Increased by +32.14% | Sep 30, 23 |
| 10 | Janus Henderson Global Life Sciences D | 348.34K (2.91%) | 111.97K Increased by +32.14% | Sep 30, 23 |
| 11 | Vanguard Small Cap Value Index Inv | 283.71K (2.37%) | 571.00 Increased by +0.20% | Nov 30, 23 |
| 12 | Janus Selection Global Life Science AUSD | 271.05K (2.26%) | 85.05K Increased by +31.38% | Sep 30, 23 |
| 13 | Janus Henderson Glb Life Scn I2 USD | 262.11K (2.19%) | -2.56K Decreased by -0.98% | Nov 30, 23 |
| 14 | Janus Henderson Triton D | 251.11K (2.10%) | 119.46K Increased by +47.57% | Sep 30, 23 |
| 15 | Janus Henderson US SMID Cap Growth | 251.11K (2.10%) | 119.46K Increased by +47.57% | Sep 30, 23 |
| 16 | Worldwide Healthcare Ord | 243.19K (2.03%) | 0.00 Increased by 0.00% | Aug 31, 23 |
| 17 | Janus Henderson Research D | 226.92K (1.89%) | 62.92K Increased by +27.73% | Sep 30, 23 |
| 18 | Janus Henderson US Research Growth Eq | 226.92K (1.89%) | 62.92K Increased by +27.73% | Sep 30, 23 |
| 19 | Vanguard Institutional Extnd Mkt Idx Tr | 223.15K (1.86%) | 2.19K Increased by +0.98% | Nov 30, 23 |
| 20 | Fidelity® Select Biotechnology | 181.11K (1.51%) | 0.00 Increased by 0.00% | Oct 31, 23 |