| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 15.91M (10.02%) | -1.14M Decreased by -7.17% | Sep 30, 23 |
| 2 | T. Rowe Price Associates, Inc. | 9.69M (6.11%) | 662.04K Increased by +6.83% | Sep 30, 23 |
| 3 | Hillhouse Capital Advisors, Ltd. | 6.44M (4.06%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 4 | RA Capital Management, LLC | 6.26M (3.95%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 5 | BlackRock Inc | 4.62M (2.91%) | -122.56K Decreased by -2.65% | Sep 30, 23 |
| 6 | Capital World Investors | 2.39M (1.50%) | -143.00 Decreased by -0.01% | Sep 30, 23 |
| 7 | Paradigm Biocapital Advisors LP | 2.03M (1.28%) | 219.76K Increased by +10.85% | Sep 30, 23 |
| 8 | Polar Capital Holdings PLC | 1.87M (1.18%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 9 | Massachusetts Financial Services Company | 1.87M (1.18%) | 212.33K Increased by +11.37% | Sep 30, 23 |
| 10 | Capital Research & Mgmt Co - Division 3 | 1.83M (1.16%) | -29.21K Decreased by -1.59% | Sep 30, 23 |
| 11 | Federated Hermes Inc | 1.76M (1.11%) | -177.02K Decreased by -10.03% | Sep 30, 23 |
| 12 | HHG PLC | 1.73M (1.09%) | -80.56K Decreased by -4.65% | Sep 30, 23 |
| 13 | Adage Capital Partners Gp LLC | 1.71M (1.08%) | 860.41K Increased by +50.36% | Sep 30, 23 |
| 14 | Westfield Capital Management Company, LP | 1.67M (1.05%) | 696.10K Increased by +41.73% | Sep 30, 23 |
| 15 | Wellington Management Company LLP | 1.34M (0.85%) | -313.84K Decreased by -23.35% | Sep 30, 23 |
| 16 | Holocene Advisors, LP | 1.27M (0.80%) | 362.21K Increased by +28.54% | Sep 30, 23 |
| 17 | Matthews International Cap Mgmt LLc | 1.12M (0.71%) | 136.00 Increased by +0.01% | Sep 30, 23 |
| 18 | AllianceBernstein L.P. | 1.10M (0.69%) | -339.01K Decreased by -30.77% | Sep 30, 23 |
| 19 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 1.07M (0.68%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 20 | Avidity Partners Management LP | 967.00K (0.61%) | 168.10K Increased by +17.38% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 3.15M (1.98%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | Fidelity Growth Compy Commingled Pl O | 2.35M (1.48%) | 13.21K Increased by +0.56% | Nov 30, 23 |
| 3 | Fidelity® Growth Company | 1.82M (1.15%) | 62.20K Increased by +3.42% | Nov 30, 23 |
| 4 | T. Rowe Price Growth Stock | 1.70M (1.07%) | 289.00K Increased by +17.00% | Sep 30, 23 |
| 5 | T. Rowe Price US Growth Stock Composite | 1.70M (1.07%) | 289.00K Increased by +17.00% | Sep 30, 23 |
| 6 | T. Rowe Price Health Sciences | 1.54M (0.97%) | -1.95K Decreased by -0.13% | Sep 30, 23 |
| 7 | Select Health Care | 1.52M (0.96%) | -181.68K Decreased by -11.97% | Oct 31, 23 |
| 8 | Fidelity Select Health Care | 1.45M (0.91%) | -68.32K Decreased by -4.71% | Nov 30, 23 |
| 9 | MFS Mid Cap Growth A | 1.34M (0.85%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 10 | MFS Mid Cap Growth Equity | 1.25M (0.79%) | 177.44K Increased by +14.16% | Sep 30, 23 |
| 11 | Vanguard Health Care Inv | 1.17M (0.74%) | -314.00K Decreased by -26.86% | Sep 30, 23 |
| 12 | T. Rowe Price Lrg Cp Gr I | 1.10M (0.69%) | -4.10K Decreased by -0.37% | Sep 30, 23 |
| 13 | T. Rowe Price US Large-Cap Growth Equity | 1.10M (0.69%) | -4.10K Decreased by -0.37% | Sep 30, 23 |
| 14 | Polar Capital Healthcare Opports Inc | 1.07M (0.67%) | -175.82K Decreased by -16.43% | Nov 30, 23 |
| 15 | T. Rowe Price Growth Stock Tr-B | 1.05M (0.66%) | 277.23K Increased by +26.31% | Sep 30, 23 |
| 16 | iShares Biotechnology ETF | 976.93K (0.62%) | -891.00 Decreased by -0.09% | Dec 29, 23 |
| 17 | American Funds New World A | 944.64K (0.60%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 18 | Fidelity® Contrafund® | 937.21K (0.59%) | -184.80K Decreased by -19.72% | Nov 30, 23 |
| 19 | Fidelity Advisor® Health Care I | 900.00K (0.57%) | -100.00K Decreased by -11.11% | Nov 30, 23 |
| 20 | Federated Hermes Kaufmann Small Cap A | 896.40K (0.56%) | -83.40K Decreased by -9.30% | Sep 30, 23 |