| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Suvretta Capital Management, LLC | 7.34M (14.85%) | 307.40K Increased by +4.19% | Sep 30, 23 |
| 2 | BlackRock Inc | 6.92M (14.01%) | 763.64K Increased by +11.03% | Sep 30, 23 |
| 3 | Bvf Inc | 6.73M (13.62%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 4 | EcoR1 Capital, LLC | 5.81M (11.75%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 5 | Deerfield Management Co | 4.37M (8.85%) | 1.14M Increased by +25.97% | Sep 30, 23 |
| 6 | Vanguard Group Inc | 3.92M (7.94%) | 275.17K Increased by +7.01% | Sep 30, 23 |
| 7 | State Street Corporation | 3.26M (6.59%) | 243.44K Increased by +7.48% | Sep 30, 23 |
| 8 | venBio Select Advisor LLC | 2.98M (6.03%) | -125.00K Decreased by -4.19% | Sep 30, 23 |
| 9 | Holocene Advisors, LP | 2.44M (4.93%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 10 | Armistice Capital, LLC | 2.24M (4.53%) | 112.00K Increased by +5.01% | Sep 30, 23 |
| 11 | Artal Group S A | 2.02M (4.08%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 12 | Prosight Management, LP | 1.93M (3.91%) | 589.10K Increased by +30.48% | Sep 30, 23 |
| 13 | Foresite Capital Management IV, LLC | 1.85M (3.74%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | Dimensional Fund Advisors, Inc. | 1.80M (3.65%) | -107.43K Decreased by -5.95% | Sep 30, 23 |
| 15 | Geode Capital Management, LLC | 1.58M (3.19%) | 249.84K Increased by +15.83% | Sep 30, 23 |
| 16 | Citadel Advisors Llc | 1.47M (2.98%) | -444.32K Decreased by -30.18% | Sep 30, 23 |
| 17 | TCG Crossover Management, LLC | 1.42M (2.88%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 18 | COMMODORE CAPITAL LP | 1.40M (2.83%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 19 | Franklin Resources Inc | 1.22M (2.48%) | -1.54K Decreased by -0.13% | Sep 30, 23 |
| 20 | Paradigm Biocapital Advisors LP | 1.21M (2.46%) | 207.92K Increased by +17.14% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.21M (4.47%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 2 | iShares Russell 2000 ETF | 1.90M (3.85%) | 12.08K Increased by +0.64% | Dec 29, 23 |
| 3 | SPDR® S&P Biotech ETF | 1.34M (2.72%) | -7.78K Decreased by -0.58% | Dec 31, 23 |
| 4 | Vanguard Institutional Extnd Mkt Idx Tr | 1.13M (2.28%) | 2.35K Increased by +0.21% | Nov 30, 23 |
| 5 | iShares Russell 2000 Value ETF | 688.98K (1.39%) | 1.28K Increased by +0.19% | Dec 29, 23 |
| 6 | Fidelity® Small Cap Index | 680.34K (1.38%) | 20.18K Increased by +2.97% | Oct 31, 23 |
| 7 | Franklin Small Cap Growth Adv | 571.70K (1.16%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 8 | Franklin US Small Cap Growth Equity | 571.70K (1.16%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 9 | iShares Biotechnology ETF | 491.15K (0.99%) | -448.00 Decreased by -0.09% | Dec 29, 23 |
| 10 | Candriam Global Equities Oncology | 467.00K (0.95%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 11 | Belfius Equities Cure C Cap | 442.00K (0.89%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 12 | Fidelity® Extended Market Index | 420.95K (0.85%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 13 | State St Russell Sm/Mid Cp® Indx NL Cl C | 420.69K (0.85%) | 37.80K Increased by +8.99% | Dec 31, 23 |
| 14 | DFA US Targeted Value I | 381.94K (0.77%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 15 | Franklin Biotechnology Discv A(acc)USD | 381.25K (0.77%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 16 | BlackRock Advantage Small Cap Core Instl | 377.89K (0.76%) | -5.92K Decreased by -1.57% | Nov 30, 23 |
| 17 | Schwab US Small-Cap ETF™ | 335.54K (0.68%) | 150.00 Increased by +0.04% | Dec 30, 23 |
| 18 | State St Russell Sm Cap® Indx SL Cl I | 266.81K (0.54%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 19 | DFA US Micro Cap I | 248.69K (0.50%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | Direxion Daily S&P Biotech Bull 3X ETF | 226.45K (0.46%) | 5.06K Increased by +2.24% | Nov 30, 23 |