| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 22.14M (10.45%) | 1.75M Increased by +7.89% | Sep 30, 23 |
| 2 | Mhr Fund Management Llc | 20.00M (9.43%) | 8.00M Increased by +40.01% | Sep 30, 23 |
| 3 | BlackRock Inc | 18.38M (8.67%) | 1.37M Increased by +7.48% | Sep 30, 23 |
| 4 | State Street Corporation | 16.73M (7.89%) | 3.17M Increased by +18.92% | Sep 30, 23 |
| 5 | Perceptive Advisors LLC | 11.96M (5.64%) | -2.07M Decreased by -17.33% | Sep 30, 23 |
| 6 | Millennium Management LLC | 7.82M (3.69%) | 4.24M Increased by +54.21% | Sep 30, 23 |
| 7 | Pictet Asset Manangement SA | 6.91M (3.26%) | 6.91M Increased by +100.00% | Sep 30, 23 |
| 8 | venBio Select Advisor LLC | 6.70M (3.16%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 9 | Artisan Partners Limited Partnership | 5.04M (2.38%) | 609.74K Increased by +12.11% | Sep 30, 23 |
| 10 | Geode Capital Management, LLC | 4.75M (2.24%) | 611.05K Increased by +12.87% | Sep 30, 23 |
| 11 | Orbimed Advisors, LLC | 4.71M (2.22%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 12 | Balyasny Asset Management LLC | 4.48M (2.11%) | 2.94M Increased by +65.61% | Sep 30, 23 |
| 13 | Dimensional Fund Advisors, Inc. | 3.98M (1.88%) | 1.88M Increased by +47.29% | Sep 30, 23 |
| 14 | Goldman Sachs Group Inc | 3.76M (1.78%) | 228.37K Increased by +6.07% | Sep 30, 23 |
| 15 | Boxer Capital LLC | 3.71M (1.75%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 16 | T. Rowe Price Associates, Inc. | 3.60M (1.70%) | -66.25K Decreased by -1.84% | Sep 30, 23 |
| 17 | MPM Oncology Impact Management LP | 3.29M (1.55%) | 337.28K Increased by +10.26% | Sep 30, 23 |
| 18 | Credit Suisse First Boston (CSFB) | 2.84M (1.34%) | 49.34K Increased by +1.74% | Sep 30, 23 |
| 19 | Candriam Luxembourg S.C.A. | 2.75M (1.30%) | 1.02M Increased by +37.12% | Sep 30, 23 |
| 20 | JPMorgan Chase & Co | 2.75M (1.30%) | 111.07K Increased by +4.04% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | SPDR® S&P Biotech ETF | 11.07M (5.22%) | -64.12K Decreased by -0.58% | Dec 31, 23 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 7.10M (3.35%) | 6.02K Increased by +0.08% | Nov 30, 23 |
| 3 | iShares Russell 2000 ETF | 6.12M (2.89%) | 38.96K Increased by +0.64% | Dec 29, 23 |
| 4 | Vanguard Small Cap Index | 5.79M (2.73%) | 17.70K Increased by +0.31% | Nov 30, 23 |
| 5 | Vanguard Small Cap Value Index Inv | 4.02M (1.90%) | 29.38K Increased by +0.73% | Nov 30, 23 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 3.09M (1.46%) | 5.59K Increased by +0.18% | Nov 30, 23 |
| 7 | Worldwide Healthcare Ord | 2.86M (1.35%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 8 | Artisan Small Cap Investor | 2.69M (1.27%) | 256.16K Increased by +9.52% | Sep 30, 23 |
| 9 | Artisan U.S. Small-Cap Growth | 2.69M (1.27%) | 256.16K Increased by +9.52% | Sep 30, 23 |
| 10 | CS (Lux) Digital Health Equity SB USD | 2.30M (1.08%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 11 | Fidelity® Small Cap Index | 2.21M (1.04%) | 60.38K Increased by +2.73% | Oct 31, 23 |
| 12 | iShares Russell 2000 Value ETF | 2.20M (1.04%) | 4.09K Increased by +0.19% | Dec 29, 23 |
| 13 | Pictet-Biotech P USD | 2.08M (0.98%) | 2.08M Increased by +100.00% | Jun 30, 23 |
| 14 | Candriam Global Equities Oncology | 1.73M (0.82%) | 790.00K Increased by +45.63% | Sep 30, 23 |
| 15 | T. Rowe Price Health Sciences | 1.73M (0.81%) | -114.84K Decreased by -6.65% | Sep 30, 23 |
| 16 | JPM Thematics Genetic Thrps C2 Acc USD | 1.60M (0.76%) | -44.40K Decreased by -2.77% | Dec 31, 23 |
| 17 | iShares Biotechnology ETF | 1.48M (0.70%) | -1.35K Decreased by -0.09% | Dec 29, 23 |
| 18 | C WorldWide Healthcare Select 1A | 1.36M (0.64%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 19 | State St Russell Sm/Mid Cp® Indx NL Cl C | 1.34M (0.63%) | 62.60K Increased by +4.67% | Dec 31, 23 |
| 20 | Direxion Daily S&P Biotech Bull 3X ETF | 1.33M (0.63%) | 48.62K Increased by +3.66% | Dec 28, 23 |