| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Viking Global Investors LP | 7.15M (32.68%) | 511.63K Increased by +7.15% | Sep 30, 23 |
| 2 | RA Capital Management, LLC | 4.72M (21.59%) | 870.34K Increased by +18.42% | Sep 30, 23 |
| 3 | Perceptive Advisors LLC | 4.26M (19.45%) | 631.92K Increased by +14.85% | Sep 30, 23 |
| 4 | BlackRock Inc | 2.54M (11.61%) | -6.83K Decreased by -0.27% | Sep 30, 23 |
| 5 | Vanguard Group Inc | 1.79M (8.18%) | 18.27K Increased by +1.02% | Sep 30, 23 |
| 6 | TCG Crossover Management, LLC | 1.75M (8.00%) | 1.75M Increased by +100.00% | Sep 30, 23 |
| 7 | State Street Corporation | 1.62M (7.39%) | -200.65K Decreased by -12.41% | Sep 30, 23 |
| 8 | Woodline Partners LP | 1.52M (6.97%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 9 | FMR Inc | 1.52M (6.94%) | -254.14K Decreased by -16.75% | Sep 30, 23 |
| 10 | Capital Research Global Investors | 1.22M (5.58%) | -530.19K Decreased by -43.40% | Sep 30, 23 |
| 11 | Loomis, Sayles & Company LP | 1.12M (5.10%) | -34.85K Decreased by -3.12% | Sep 30, 23 |
| 12 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 966.00K (4.41%) | 7.12K Increased by +0.74% | Sep 30, 23 |
| 13 | Sofinnova Ventures | 743.29K (3.40%) | -254.99K Decreased by -34.31% | Sep 30, 23 |
| 14 | Geode Capital Management, LLC | 646.16K (2.95%) | -12.86K Decreased by -1.99% | Sep 30, 23 |
| 15 | Soleus Capital Management, L.P. | 549.18K (2.51%) | 76.00K Increased by +13.84% | Sep 30, 23 |
| 16 | Eventide Asset Management, LLC | 434.03K (1.98%) | 434.03K Increased by +100.00% | Sep 30, 23 |
| 17 | Morgan Stanley - Brokerage Accounts | 382.77K (1.75%) | -1.89K Decreased by -0.49% | Sep 30, 23 |
| 18 | JPMorgan Chase & Co | 369.99K (1.69%) | 3.09K Increased by +0.83% | Sep 30, 23 |
| 19 | Northern Trust Corp | 315.42K (1.44%) | -13.58K Decreased by -4.31% | Sep 30, 23 |
| 20 | Two Sigma Advisers, LLC | 310.20K (1.42%) | 17.20K Increased by +5.54% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.10M (5.02%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 2 | American Funds SMALLCAP World A | 1.08M (4.94%) | -408.11K Decreased by -37.77% | Sep 30, 23 |
| 3 | SPDR® S&P Biotech ETF | 915.86K (4.19%) | -5.31K Decreased by -0.58% | Dec 31, 23 |
| 4 | iShares Russell 2000 ETF | 915.42K (4.18%) | 5.80K Increased by +0.63% | Dec 29, 23 |
| 5 | Fidelity Growth Compy Commingled Pl O | 653.85K (2.99%) | 3.06K Increased by +0.47% | Nov 30, 23 |
| 6 | Loomis Sayles Small Cap Growth Instl | 635.61K (2.90%) | -15.10K Decreased by -2.38% | Nov 30, 23 |
| 7 | Eventide Healthcare & Life Sciences I | 434.03K (1.98%) | 434.03K Increased by +100.00% | Sep 30, 23 |
| 8 | Fidelity® Growth Company | 392.28K (1.79%) | 14.40K Increased by +3.67% | Nov 30, 23 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 363.41K (1.66%) | 753.00 Increased by +0.21% | Nov 30, 23 |
| 10 | Fidelity® Small Cap Index | 329.18K (1.50%) | 8.93K Increased by +2.71% | Oct 31, 23 |
| 11 | iShares Biotechnology ETF | 257.49K (1.18%) | -235.00 Decreased by -0.09% | Dec 29, 23 |
| 12 | ArrowMark Small Cap Gro | 217.39K (0.99%) | 217.39K Increased by +100.00% | Sep 30, 23 |
| 13 | Meridian Small Cap Growth Legacy | 217.39K (0.99%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | State St Russell Sm/Mid Cp® Indx NL Cl C | 202.54K (0.93%) | 9.50K Increased by +4.69% | Dec 31, 23 |
| 15 | iShares Russell 2000 Growth ETF | 201.38K (0.92%) | 0.00 Increased by 0.00% | Dec 29, 23 |
| 16 | Fidelity® Select Biotechnology | 187.61K (0.86%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 17 | Russell Inv Tax-Managed US Mid&Sm Cap S | 175.57K (0.80%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 18 | Loomis Sayles Small Cap Growth CIT D | 169.86K (0.78%) | 14.54K Increased by +8.56% | Sep 30, 23 |
| 19 | Fidelity® Growth Company K6 | 160.84K (0.74%) | -17.46K Decreased by -10.86% | Nov 30, 23 |
| 20 | Schroder Global Healthcare A Acc | 159.03K (0.73%) | -34.36K Decreased by -21.60% | Sep 30, 23 |