| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 25.47M (10.28%) | 984.79K Increased by +3.87% | Dec 31, 23 |
| 2 | RA Capital Management, LLC | 23.75M (9.58%) | 10.43M Increased by +43.91% | Dec 31, 23 |
| 3 | BlackRock Inc | 21.82M (8.81%) | 1.55M Increased by +7.10% | Dec 31, 23 |
| 4 | Redmile Group, LLC | 17.50M (7.06%) | -227.00K Decreased by -1.30% | Sep 30, 23 |
| 5 | Wellington Management Company LLP | 13.26M (5.35%) | 3.51M Increased by +26.44% | Sep 30, 23 |
| 6 | HHG PLC | 11.04M (4.46%) | -6.64M Decreased by -60.13% | Dec 31, 23 |
| 7 | State Street Corporation | 8.08M (3.26%) | -1.48M Decreased by -18.28% | Dec 31, 23 |
| 8 | D. E. Shaw & Co LP | 7.00M (2.82%) | 714.72K Increased by +10.22% | Sep 30, 23 |
| 9 | Fairmount Funds Management LLC | 5.93M (2.39%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 10 | FMR Inc | 5.79M (2.34%) | 175.81K Increased by +3.04% | Sep 30, 23 |
| 11 | Pentwater Capital Management LP | 5.66M (2.28%) | 5.66M Increased by +100.00% | Dec 31, 23 |
| 12 | NORGES BANK | 5.54M (2.23%) | 5.54M Increased by +100.00% | Dec 31, 23 |
| 13 | Geode Capital Management, LLC | 5.38M (2.17%) | 482.90K Increased by +8.97% | Dec 31, 23 |
| 14 | Fidelity International Ltd | 5.36M (2.16%) | 5.36M Increased by +100.00% | Dec 31, 23 |
| 15 | Millennium Management LLC | 4.47M (1.81%) | 2.87M Increased by +64.11% | Dec 31, 23 |
| 16 | Morgan Stanley - Brokerage Accounts | 4.11M (1.66%) | -719.91K Decreased by -17.52% | Dec 31, 23 |
| 17 | T. Rowe Price Associates, Inc. | 3.91M (1.58%) | 1.58M Increased by +40.55% | Sep 30, 23 |
| 18 | Artisan Partners Limited Partnership | 3.72M (1.50%) | -1.34K Decreased by -0.04% | Sep 30, 23 |
| 19 | Pictet Asset Manangement SA | 3.71M (1.50%) | 3.71M Increased by +100.00% | Sep 30, 23 |
| 20 | Nuveen Asset Management, LLC | 3.11M (1.25%) | 465.50K Increased by +14.98% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 7.79M (3.14%) | 10.70K Increased by +0.14% | Nov 30, 23 |
| 2 | Vanguard Small Cap Index | 6.45M (2.60%) | 29.84K Increased by +0.46% | Nov 30, 23 |
| 3 | iShares Russell 2000 ETF | 6.40M (2.58%) | 40.72K Increased by +0.64% | Dec 29, 23 |
| 4 | Vanguard Health Care Inv | 6.29M (2.54%) | 3.79M Increased by +60.32% | Sep 30, 23 |
| 5 | Janus Henderson Global Life Sciences D | 3.68M (1.49%) | -37.38K Decreased by -1.02% | Sep 30, 23 |
| 6 | Vanguard Small Cap Growth Index Inv | 3.61M (1.46%) | 18.11K Increased by +0.50% | Nov 30, 23 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 3.24M (1.31%) | 28.79K Increased by +0.89% | Nov 30, 23 |
| 8 | Fidelity Canadian Large Cap Sr B | 3.20M (1.29%) | 3.20M Increased by +100.00% | Dec 31, 23 |
| 9 | Janus Henderson Global Life Sciences | 2.80M (1.13%) | -881.51K Decreased by -31.48% | Dec 31, 23 |
| 10 | SPDR® S&P Biotech ETF | 2.73M (1.10%) | -15.80K Decreased by -0.58% | Dec 31, 23 |
| 11 | Fidelity Small Cap Index | 2.42M (0.98%) | 38.50K Increased by +1.59% | Jan 31, 24 |
| 12 | Janus Henderson Triton D | 2.39M (0.96%) | 1.15M Increased by +48.02% | Sep 30, 23 |
| 13 | Janus Henderson Glb Life Scn I2 USD | 2.34M (0.94%) | -444.43K Decreased by -19.01% | Nov 30, 23 |
| 14 | Fidelity® Small Cap Index | 2.31M (0.93%) | 62.30K Increased by +2.70% | Oct 31, 23 |
| 15 | Artisan International Small-Mid Investor | 2.30M (0.93%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 16 | Artisan Non-U.S. Small-Mid Growth Comp | 2.30M (0.93%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 17 | Janus Selection Global Life Science AUSD | 2.11M (0.85%) | -715.18K Decreased by -33.82% | Dec 31, 23 |
| 18 | BioPharma Credit Ord | 1.99M (0.80%) | 1.99M Increased by +100.00% | Jun 30, 23 |
| 19 | iShares Biotechnology ETF | 1.93M (0.78%) | -1.76K Decreased by -0.09% | Dec 29, 23 |
| 20 | Fidelity Growth Compy Commingled Pl O | 1.72M (0.69%) | -82.54K Decreased by -4.81% | Nov 30, 23 |