| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RTW INVESTMENTS, LLC | 6.10M (19.68%) | 66.75K Increased by +1.09% | Sep 30, 23 |
| 2 | Wellington Management Company LLP | 3.91M (12.63%) | 217.92K Increased by +5.57% | Sep 30, 23 |
| 3 | Rock Springs Capital Management LP | 2.94M (9.50%) | -84.70K Decreased by -2.88% | Sep 30, 23 |
| 4 | T. Rowe Price Associates, Inc. | 2.52M (8.14%) | 97.86K Increased by +3.88% | Sep 30, 23 |
| 5 | Baker Bros Advisors LP | 2.52M (8.14%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 6 | FMR Inc | 2.14M (6.89%) | 90.12K Increased by +4.22% | Sep 30, 23 |
| 7 | Paradigm Biocapital Advisors LP | 1.38M (4.47%) | 114.56K Increased by +8.27% | Sep 30, 23 |
| 8 | Morgan Stanley - Brokerage Accounts | 961.09K (3.10%) | 148.47K Increased by +15.45% | Sep 30, 23 |
| 9 | General Atlantic Llc | 950.00K (3.07%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 10 | Pictet Asset Manangement SA | 910.24K (2.94%) | 910.24K Increased by +100.00% | Sep 30, 23 |
| 11 | BRAIDWELL LP | 906.97K (2.93%) | 438.95K Increased by +48.40% | Sep 30, 23 |
| 12 | BlackRock Inc | 759.83K (2.45%) | -32.25K Decreased by -4.24% | Sep 30, 23 |
| 13 | Fiera Capital Corporation | 679.80K (2.19%) | 158.50K Increased by +23.32% | Sep 30, 23 |
| 14 | First Manhattan Co. LLC | 613.75K (1.98%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | Bill & Melinda Gates Foundation | 576.92K (1.86%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 16 | Wagonhound Investments, LP | 512.86K (1.66%) | 508.15K Increased by +99.08% | Sep 30, 23 |
| 17 | Principal Financial Group Inc | 485.89K (1.57%) | 2.13K Increased by +0.44% | Sep 30, 23 |
| 18 | COWEN AND COMPANY, LLC | 460.04K (1.48%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 19 | Renaissance Technologies Corp | 456.30K (1.47%) | 9.00K Increased by +1.97% | Sep 30, 23 |
| 20 | Logos Global Management LP | 450.00K (1.45%) | -50.00K Decreased by -11.11% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 2.09M (6.73%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | T. Rowe Price Health Sciences | 1.73M (5.58%) | 70.41K Increased by +4.07% | Sep 30, 23 |
| 3 | Polar Capital Biotech S Inc | 530.00K (1.71%) | 180.00K Increased by +33.96% | Nov 30, 23 |
| 4 | Pictet-Biotech P USD | 443.19K (1.43%) | 1.50K Increased by +0.34% | Jun 30, 23 |
| 5 | BlackRock Health Sciences Term Trust | 381.77K (1.23%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 6 | Fidelity® Small Cap Growth | 313.38K (1.01%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 7 | Fiera SMID Growth | 311.79K (1.01%) | 89.30K Increased by +28.64% | Sep 30, 23 |
| 8 | UBS: US Equity Small Cap Growth | 300.16K (0.97%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 9 | Pictet-Global Megatrend Sel I USD | 278.39K (0.90%) | -1.10K Decreased by -0.39% | Jun 30, 23 |
| 10 | US Small-Cap Growth II Equity Comp | 267.30K (0.86%) | 267.30K Increased by +100.00% | Jun 30, 23 |
| 11 | T. Rowe Price New Horizons | 267.20K (0.86%) | -100.00 Decreased by -0.04% | Sep 30, 23 |
| 12 | Wellington Global Hlthcr Eq USD G Ac | 259.61K (0.84%) | -1.89K Decreased by -0.73% | Nov 30, 23 |
| 13 | iShares Biotechnology ETF | 254.65K (0.82%) | -232.00 Decreased by -0.09% | Dec 29, 23 |
| 14 | Fidelity Global Innovators Cl F | 235.37K (0.76%) | 428.00 Increased by +0.18% | Sep 30, 23 |
| 15 | Candriam Global Equities Oncology | 218.00K (0.70%) | -57.00K Decreased by -26.15% | Sep 30, 23 |
| 16 | Fidelity® Select Biotechnology | 207.72K (0.67%) | -18.10K Decreased by -8.71% | Nov 30, 23 |
| 17 | MFS New Discovery I | 205.44K (0.66%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 18 | Fidelity Growth Compy Commingled Pl O | 200.32K (0.65%) | 886.00 Increased by +0.44% | Nov 30, 23 |
| 19 | BGF World Healthscience A2 | 198.56K (0.64%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 20 | VIP Growth Initial | 183.85K (0.59%) | 0.00 Increased by 0.00% | Nov 30, 23 |