| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Associates, Inc. | 3.24M (0.21%) | 11.85K Increased by +0.37% | Sep 30, 23 |
| 2 | Baker Bros Advisors LP | 3.16M (0.21%) | 554.00 Increased by +0.02% | Sep 30, 23 |
| 3 | Redmile Group, LLC | 2.97M (0.20%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 4 | Artal Group S A | 2.52M (0.17%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 5 | FMR Inc | 2.14M (0.14%) | 1.85K Increased by +0.09% | Sep 30, 23 |
| 6 | RA Capital Management, LLC | 937.50K (0.06%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 7 | Vanguard Group Inc | 900.01K (0.06%) | 202.72K Increased by +22.52% | Sep 30, 23 |
| 8 | BlackRock Inc | 870.92K (0.06%) | 13.74K Increased by +1.58% | Sep 30, 23 |
| 9 | Millennium Management LLC | 768.06K (0.05%) | -216.60K Decreased by -28.20% | Sep 30, 23 |
| 10 | Great Point Partners LLC | 615.32K (0.04%) | 115.32K Increased by +18.74% | Sep 30, 23 |
| 11 | Goldman Sachs Group Inc | 456.99K (0.03%) | -215.20K Decreased by -47.09% | Sep 30, 23 |
| 12 | ExodusPoint Capital Management, LP | 453.90K (0.03%) | 453.90K Increased by +100.00% | Sep 30, 23 |
| 13 | Geode Capital Management, LLC | 292.53K (0.02%) | 72.11K Increased by +24.65% | Sep 30, 23 |
| 14 | State Street Corporation | 289.10K (0.02%) | 27.85K Increased by +9.63% | Sep 30, 23 |
| 15 | Opaleye Management Inc | 261.00K (0.02%) | 197.50K Increased by +75.67% | Sep 30, 23 |
| 16 | Hudson Bay Capital Management LP | 248.52K (0.02%) | 248.52K Increased by +100.00% | Sep 30, 23 |
| 17 | Rhenman Partners Asset Management AB | 200.00K (0.01%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 18 | Candriam Luxembourg S.C.A. | 175.01K (0.01%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 19 | First Manhattan Co. LLC | 172.20K (0.01%) | 172.20K Increased by +100.00% | Sep 30, 23 |
| 20 | Samsara BioCapital, LLC | 154.66K (0.01%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | US Small-Cap Growth II Equity Comp | 1.87M (0.12%) | 1.87M Increased by +100.00% | Jun 30, 23 |
| 2 | T. Rowe Price New Horizons | 1.87M (0.12%) | -644.00 Decreased by -0.03% | Sep 30, 23 |
| 3 | Fidelity® Select Biotechnology | 1.69M (0.11%) | -147.50K Decreased by -8.74% | Nov 30, 23 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 460.33K (0.03%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 5 | T. Rowe Price Health Sciences | 448.10K (0.03%) | -12.72K Decreased by -2.84% | Sep 30, 23 |
| 6 | iShares Russell 2000 ETF | 328.46K (0.02%) | 2.11K Increased by +0.64% | Dec 29, 23 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 311.77K (0.02%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 8 | UBS: US Equity Small Cap Growth | 291.93K (0.02%) | 0.00 Increased by 0.00% | Jun 30, 23 |
| 9 | T. Rowe Price New Horizons Tr-Z | 266.88K (0.02%) | -228.00 Decreased by -0.09% | Sep 30, 23 |
| 10 | Rhenman Healthcare Equity L/S RC2 SEK | 200.00K (0.01%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 11 | Belfius Equities Cure C Cap | 175.00K (0.01%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 12 | Candriam Global Equities Oncology | 175.00K (0.01%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | T. Rowe Price Integrated US Sm Gr Eq | 143.15K (0.01%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | TRP Integrated US Small-Cap Gr Eq | 143.15K (0.01%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | iShares Biotechnology ETF | 136.81K (0.01%) | 504.00 Increased by +0.37% | Nov 30, 23 |
| 16 | iShares Russell 2000 Value ETF | 134.72K (0.01%) | 252.00 Increased by +0.19% | Dec 29, 23 |
| 17 | Bruce | 120.00K (0.01%) | 65.00K Increased by +54.17% | Sep 30, 23 |
| 18 | Fidelity® Small Cap Index | 114.95K (0.01%) | 1.18K Increased by +1.03% | Oct 31, 23 |
| 19 | Fidelity® Extended Market Index | 99.48K (0.01%) | 18.69K Increased by +18.79% | Nov 30, 23 |
| 20 | State St Russell Sm/Mid Cp® Indx NL Cl C | 93.13K (0.01%) | 15.90K Increased by +17.07% | Dec 31, 23 |