| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bvf Inc | 5.68M (9.67%) | 3.23M Increased by +56.80% | Jun 30, 23 |
| 2 | BlackRock Inc | 4.36M (7.41%) | 806.60K Increased by +18.52% | Jun 30, 23 |
| 3 | Federated Hermes Inc | 3.39M (5.77%) | 525.09K Increased by +15.49% | Jun 30, 23 |
| 4 | Avidity Partners Management LP | 2.99M (5.08%) | -687.70K Decreased by -23.03% | Jun 30, 23 |
| 5 | Vanguard Group Inc | 2.83M (4.81%) | 508.65K Increased by +17.98% | Jun 30, 23 |
| 6 | Canaan Partners X LLC | 2.66M (4.53%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 7 | Adage Capital Partners Gp LLC | 2.58M (4.38%) | -101.45K Decreased by -3.94% | Jun 30, 23 |
| 8 | T. Rowe Price Associates, Inc. | 2.50M (4.26%) | 1.04M Increased by +41.40% | Jun 30, 23 |
| 9 | Deerfield Management Co | 2.27M (3.86%) | 525.00K Increased by +23.14% | Jun 30, 23 |
| 10 | Boxer Capital LLC | 2.20M (3.75%) | 0.00 Increased by 0.00% | Jun 30, 23 |
| 11 | State Street Corporation | 2.14M (3.64%) | 24.19K Increased by +1.13% | Jun 30, 23 |
| 12 | Logos Global Management LP | 1.75M (2.98%) | -1.85M Decreased by -105.71% | Jun 30, 23 |
| 13 | HHG PLC | 1.67M (2.84%) | 1.01M Increased by +60.55% | Jun 30, 23 |
| 14 | Citadel Advisors Llc | 1.15M (1.96%) | 142.31K Increased by +12.34% | Jun 30, 23 |
| 15 | FMR Inc | 1.10M (1.87%) | -66.14K Decreased by -6.03% | Jun 30, 23 |
| 16 | Dimensional Fund Advisors, Inc. | 1.09M (1.85%) | 49.90K Increased by +4.59% | Jun 30, 23 |
| 17 | Baker Bros Advisors LP | 1.06M (1.81%) | 229.35K Increased by +21.59% | Jun 30, 23 |
| 18 | Geode Capital Management, LLC | 1.02M (1.74%) | 162.82K Increased by +15.92% | Jun 30, 23 |
| 19 | Junked Platinum Investment Management Ltd | 814.67K (1.39%) | -20.85K Decreased by -2.56% | Jun 30, 23 |
| 20 | COMMODORE CAPITAL LP | 775.00K (1.32%) | 775.00K Increased by +100.00% | Jun 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Federated Hermes Kaufmann Small Cap A | 1.87M (3.18%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | Federated Hermes Kaufmann Small Cap Grow | 1.87M (3.18%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.86M (3.17%) | 3.44K Increased by +0.18% | Nov 30, 23 |
| 4 | SPDR® S&P Biotech ETF | 1.72M (2.92%) | -9.94K Decreased by -0.58% | Dec 31, 23 |
| 5 | iShares Russell 2000 ETF | 1.61M (2.73%) | 10.23K Increased by +0.64% | Dec 29, 23 |
| 6 | T. Rowe Price New Horizons | 1.59M (2.70%) | 84.88K Increased by +5.34% | Sep 30, 23 |
| 7 | US Small-Cap Growth II Equity Comp | 1.51M (2.56%) | 1.51M Increased by +100.00% | Jun 30, 23 |
| 8 | Federated Hermes Kaufmann Growth | 1.48M (2.51%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 9 | Federated Hermes Kaufmann R | 1.48M (2.51%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 10 | American Funds SMALLCAP World A | 1.18M (2.00%) | 502.30K Increased by +42.61% | Sep 30, 23 |
| 11 | Fidelity® Select Biotechnology | 916.96K (1.56%) | -178.00K Decreased by -19.41% | Nov 30, 23 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 834.77K (1.42%) | 1.46K Increased by +0.18% | Nov 30, 23 |
| 13 | UBS: US Equity Small Cap Growth | 606.96K (1.03%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | Fidelity® Small Cap Index | 523.59K (0.89%) | 13.86K Increased by +2.65% | Oct 31, 23 |
| 15 | Janus Henderson Glb Life Scn I2 USD | 515.24K (0.88%) | 189.70K Increased by +36.82% | Nov 30, 23 |
| 16 | Janus Henderson Global Life Sciences | 415.75K (0.71%) | 26.39K Increased by +6.35% | Sep 30, 23 |
| 17 | Janus Henderson Global Life Sciences D | 415.75K (0.71%) | 26.39K Increased by +6.35% | Sep 30, 23 |
| 18 | iShares Biotechnology ETF | 403.02K (0.69%) | -367.00 Decreased by -0.09% | Dec 29, 23 |
| 19 | Belfius Equities Cure C Cap | 400.00K (0.68%) | -10.00K Decreased by -2.50% | Sep 30, 23 |
| 20 | Candriam Global Equities Oncology | 400.00K (0.68%) | -10.00K Decreased by -2.50% | Sep 30, 23 |