| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | EcoR1 Capital, LLC | 5.76M (14.86%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | FMR Inc | 4.32M (11.14%) | 28.50K Increased by +0.66% | Sep 30, 23 |
| 3 | Bvf Inc | 1.92M (4.94%) | -250.00K Decreased by -13.05% | Sep 30, 23 |
| 4 | Stonepine Capital Management Llc | 802.54K (2.07%) | 119.88K Increased by +14.94% | Sep 30, 23 |
| 5 | Segall Bryant & Hamill | 737.99K (1.90%) | 346.63K Increased by +46.97% | Sep 30, 23 |
| 6 | Prosight Management, LP | 730.21K (1.88%) | 312.71K Increased by +42.82% | Sep 30, 23 |
| 7 | Hudson Bay Capital Management LP | 700.00K (1.81%) | 375.00K Increased by +53.57% | Sep 30, 23 |
| 8 | PRIMECAP Management Company | 669.68K (1.73%) | 3.30K Increased by +0.49% | Sep 30, 23 |
| 9 | Wellington Management Company LLP | 476.67K (1.23%) | -48.06K Decreased by -10.08% | Sep 30, 23 |
| 10 | Citadel Advisors Llc | 469.87K (1.21%) | 236.58K Increased by +50.35% | Sep 30, 23 |
| 11 | Finepoint Capital LP | 458.66K (1.18%) | 51.80K Increased by +11.29% | Sep 30, 23 |
| 12 | BlackRock Inc | 440.61K (1.14%) | -41.26K Decreased by -9.36% | Sep 30, 23 |
| 13 | Renaissance Technologies Corp | 281.80K (0.73%) | -26.10K Decreased by -9.26% | Sep 30, 23 |
| 14 | Newtyn Management LLC | 275.00K (0.71%) | 5.00K Increased by +1.82% | Sep 30, 23 |
| 15 | Point72 Asset Management, L.P. | 173.30K (0.45%) | -707.37K Decreased by -408.18% | Sep 30, 23 |
| 16 | Greenlight Capital, Inc | 156.38K (0.40%) | 6.21K Increased by +3.97% | Sep 30, 23 |
| 17 | AlphaCentric Advisors, LLC | 105.00K (0.27%) | 6.00K Increased by +5.71% | Sep 30, 23 |
| 18 | Citigroup Inc | 90.69K (0.23%) | 89.45K Increased by +98.64% | Sep 30, 23 |
| 19 | TANG CAPITAL MANAGEMENT LLC | 89.65K (0.23%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 20 | Ameriprise Financial Inc | 89.34K (0.23%) | 39.20K Increased by +43.87% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity® Contrafund® | 1.24M (3.21%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 2 | PRIMECAP Odyssey Aggressive Growth | 562.13K (1.45%) | 3.30K Increased by +0.59% | Sep 30, 23 |
| 3 | Fidelity Contrafund Commingled Pl O | 534.28K (1.38%) | 1.22K Increased by +0.23% | Nov 30, 23 |
| 4 | VIP Growth Initial | 453.50K (1.17%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 5 | Fidelity Advisor® Equity Growth I | 404.33K (1.04%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 6 | iShares Biotechnology ETF | 358.20K (0.92%) | -327.00 Decreased by -0.09% | Dec 29, 23 |
| 7 | Fidelity® Capital Appreciation | 354.70K (0.92%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 8 | Fidelity® Contrafund® K6 | 335.75K (0.87%) | -1.22K Decreased by -0.36% | Nov 30, 23 |
| 9 | Wellington Global Hlthcr Eq USD G Ac | 280.63K (0.72%) | -2.04K Decreased by -0.73% | Nov 30, 23 |
| 10 | Segall Bryant & Hamill Sm Cp Val Ins | 252.89K (0.65%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 11 | Fidelity® Growth Discovery | 207.25K (0.53%) | 10.50K Increased by +5.07% | Nov 30, 23 |
| 12 | Fidelity Advisor® New Insights I | 173.94K (0.45%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 13 | VIP Contrafund Initial | 143.88K (0.37%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 14 | Vanguard US Opportunities Ins USD Acc | 107.55K (0.28%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | AlphaCentric LifeSci Healthcare I | 105.00K (0.27%) | 6.00K Increased by +5.71% | Sep 30, 23 |
| 16 | VP Partners Small Cap Value 3 | 103.08K (0.27%) | 4.96K Increased by +4.81% | Nov 30, 23 |
| 17 | Fidelity® Series Opportunistic Insights | 78.68K (0.20%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 18 | BlackRock Health Sciences Term Trust | 74.41K (0.19%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 19 | Pacific Select Large-Cap Growth I | 71.60K (0.18%) | -3.60K Decreased by -5.03% | Dec 31, 23 |
| 20 | Fidelity Advisor® Series Equity Gr | 58.19K (0.15%) | -3.10K Decreased by -5.33% | Nov 30, 23 |