| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 16.50M (15.12%) | -333.56K Decreased by -2.02% | Sep 30, 23 |
| 2 | Vanguard Group Inc | 10.59M (9.71%) | 274.29K Increased by +2.59% | Sep 30, 23 |
| 3 | BlackRock Inc | 7.84M (7.19%) | 242.83K Increased by +3.10% | Sep 30, 23 |
| 4 | JPMorgan Chase & Co | 6.05M (5.54%) | 178.99K Increased by +2.96% | Sep 30, 23 |
| 5 | Wellington Management Company LLP | 4.24M (3.89%) | 449.66K Increased by +10.61% | Sep 30, 23 |
| 6 | Rock Springs Capital Management LP | 3.87M (3.54%) | 61.50K Increased by +1.59% | Sep 30, 23 |
| 7 | Bellevue Group AG | 3.68M (3.37%) | 228.79K Increased by +6.22% | Sep 30, 23 |
| 8 | Granahan Investment Management Inc.. | 2.95M (2.71%) | 39.66K Increased by +1.34% | Sep 30, 23 |
| 9 | Orbimed Advisors, LLC | 2.90M (2.65%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 10 | Blair William & Co | 2.85M (2.61%) | 399.88K Increased by +14.03% | Sep 30, 23 |
| 11 | Engaged Capital LLC | 2.83M (2.60%) | 1.09M Increased by +38.32% | Sep 30, 23 |
| 12 | RA Capital Management, LLC | 2.74M (2.51%) | 2.74M Increased by +100.00% | Sep 30, 23 |
| 13 | Eventide Asset Management, LLC | 2.64M (2.42%) | 796.00 Increased by +0.03% | Sep 30, 23 |
| 14 | William Blair Investment Management, LLC | 2.62M (2.40%) | -48.51K Decreased by -1.85% | Sep 30, 23 |
| 15 | State Street Corporation | 2.34M (2.14%) | 131.81K Increased by +5.64% | Sep 30, 23 |
| 16 | Holocene Advisors, LP | 2.29M (2.10%) | 338.47K Increased by +14.80% | Sep 30, 23 |
| 17 | Dimensional Fund Advisors, Inc. | 2.23M (2.04%) | -218.08K Decreased by -9.79% | Sep 30, 23 |
| 18 | Geode Capital Management, LLC | 2.22M (2.03%) | 241.34K Increased by +10.88% | Sep 30, 23 |
| 19 | Loomis, Sayles & Company LP | 2.04M (1.87%) | -196.81K Decreased by -9.63% | Sep 30, 23 |
| 20 | Amvescap Plc. | 1.93M (1.77%) | -1.08M Decreased by -56.15% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.38M (3.10%) | 5.00K Increased by +0.15% | Nov 30, 23 |
| 2 | Vanguard Health Care Inv | 3.19M (2.92%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 3 | iShares Russell 2000 ETF | 2.94M (2.69%) | 18.70K Increased by +0.64% | Dec 29, 23 |
| 4 | Vanguard Small Cap Index | 2.78M (2.55%) | 8.55K Increased by +0.31% | Nov 30, 23 |
| 5 | Select Health Care | 2.02M (1.85%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 6 | Worldwide Healthcare Ord | 1.99M (1.82%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 7 | JPM Global Healthcare C (acc) USD | 1.94M (1.78%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 8 | JPMorgan Small Cap Growth A | 1.93M (1.77%) | -104.60K Decreased by -5.42% | Nov 30, 23 |
| 9 | Select Medical Tech and Devcs | 1.90M (1.74%) | -356.50K Decreased by -18.73% | Nov 30, 23 |
| 10 | Fidelity Select Health Care | 1.85M (1.69%) | -171.40K Decreased by -9.27% | Nov 30, 23 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 1.60M (1.47%) | 10.50K Increased by +0.65% | Nov 30, 23 |
| 12 | Bellevue Healthcare Ord | 1.58M (1.45%) | 0.00 Increased by 0.00% | May 31, 23 |
| 13 | Vanguard Small Cap Growth Index Inv | 1.56M (1.43%) | 7.91K Increased by +0.51% | Nov 30, 23 |
| 14 | CS (Lux) Digital Health Equity SB USD | 1.50M (1.37%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 15 | Eventide Gilead N | 1.34M (1.23%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 16 | Eventide Healthcare & Life Sciences I | 1.30M (1.19%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 17 | Fidelity Advisor® Health Care I | 1.20M (1.10%) | -196.77K Decreased by -16.35% | Nov 30, 23 |
| 18 | Fidelity® Small Cap Index | 1.07M (0.98%) | 31.09K Increased by +2.92% | Oct 31, 23 |
| 19 | Strategic Advisers® Fidelity US TtlStk | 1.04M (0.96%) | -32.84K Decreased by -3.15% | Nov 30, 23 |
| 20 | Fidelity® Puritan® | 976.60K (0.90%) | 0.00 Increased by 0.00% | Oct 31, 23 |