| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 7.09M (17.29%) | 1.25K Increased by +0.02% | Sep 30, 23 |
| 2 | Wellington Management Company LLP | 5.43M (13.25%) | 300.41K Increased by +5.53% | Sep 30, 23 |
| 3 | RTW INVESTMENTS, LLC | 3.46M (8.45%) | 378.99K Increased by +10.94% | Jun 30, 23 |
| 4 | BlackRock Inc | 3.25M (7.93%) | 29.97K Increased by +0.92% | Sep 30, 23 |
| 5 | Kynam Capital Management, LP | 3.20M (7.80%) | 600.00K Increased by +18.75% | Sep 30, 23 |
| 6 | Vanguard Group Inc | 2.62M (6.39%) | 20.69K Increased by +0.79% | Sep 30, 23 |
| 7 | Polar Capital Holdings PLC | 2.43M (5.92%) | 10.00K Increased by +0.41% | Sep 30, 23 |
| 8 | State Street Corporation | 2.29M (5.59%) | -434.45K Decreased by -18.95% | Sep 30, 23 |
| 9 | Bellevue Group AG | 1.90M (4.63%) | 100.00K Increased by +5.26% | Sep 30, 23 |
| 10 | Redmile Group, LLC | 1.64M (3.99%) | -60.07K Decreased by -3.67% | Sep 30, 23 |
| 11 | Eventide Asset Management, LLC | 1.60M (3.90%) | 222.26K Increased by +13.89% | Sep 30, 23 |
| 12 | Point72 Asset Management, L.P. | 1.34M (3.27%) | 157.60K Increased by +11.74% | Sep 30, 23 |
| 13 | Geode Capital Management, LLC | 1.00M (2.44%) | 35.35K Increased by +3.53% | Sep 30, 23 |
| 14 | Octagon Capital Advisors LP | 759.90K (1.85%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | COMMODORE CAPITAL LP | 706.66K (1.72%) | 75.00K Increased by +10.61% | Sep 30, 23 |
| 16 | Eversept Partners, LLC | 588.14K (1.43%) | -197.60K Decreased by -33.60% | Sep 30, 23 |
| 17 | Marshall Wace Asset Management Ltd | 538.32K (1.31%) | 248.80K Increased by +46.22% | Sep 30, 23 |
| 18 | Morgan Stanley - Brokerage Accounts | 523.70K (1.28%) | 385.92K Increased by +73.69% | Sep 30, 23 |
| 19 | Rock Springs Capital Management LP | 500.10K (1.22%) | 78.49K Increased by +15.69% | Sep 30, 23 |
| 20 | Northern Trust Corp | 473.92K (1.16%) | -13.83K Decreased by -2.92% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 1.90M (4.63%) | 100.00K Increased by +5.26% | Sep 30, 23 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.72M (4.18%) | 221.56K Increased by +12.92% | Nov 30, 23 |
| 3 | Polar Capital Biotech S Inc | 1.65M (4.02%) | 147.28K Increased by +8.94% | Nov 30, 23 |
| 4 | Eventide Healthcare & Life Sciences I | 1.60M (3.90%) | 222.26K Increased by +13.89% | Sep 30, 23 |
| 5 | Vanguard Health Care Inv | 1.38M (3.38%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 6 | SPDR® S&P Biotech ETF | 1.31M (3.20%) | -7.61K Decreased by -0.58% | Dec 31, 23 |
| 7 | Vanguard Explorer Inv | 1.30M (3.18%) | 218.34K Increased by +16.76% | Sep 30, 23 |
| 8 | iShares Russell 2000 ETF | 1.27M (3.11%) | 34.50K Increased by +2.71% | Dec 29, 23 |
| 9 | Fidelity Advisor® Biotechnology I | 1.07M (2.62%) | -257.15K Decreased by -23.94% | Nov 30, 23 |
| 10 | Pictet-Biotech P USD | 942.07K (2.30%) | 158.71K Increased by +16.85% | Jun 30, 23 |
| 11 | Fidelity Advisor® Growth Opps M | 915.90K (2.23%) | 111.90K Increased by +12.22% | Nov 30, 23 |
| 12 | Fidelity® Select Biotechnology | 907.20K (2.21%) | 184.00K Increased by +20.28% | Nov 30, 23 |
| 13 | Select Health Care | 800.00K (1.95%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 781.85K (1.91%) | 102.34K Increased by +13.09% | Nov 30, 23 |
| 15 | Fidelity Select Health Care | 700.00K (1.71%) | -100.00K Decreased by -14.29% | Nov 30, 23 |
| 16 | Polar Capital Healthcare Opports Inc | 691.70K (1.69%) | 105.01K Increased by +15.18% | Nov 30, 23 |
| 17 | Pictet-Global Megatrend Sel I USD | 575.95K (1.40%) | 99.07K Increased by +17.20% | Jun 30, 23 |
| 18 | Fidelity® Small Cap Growth | 531.38K (1.30%) | -645.00 Decreased by -0.12% | Oct 31, 23 |
| 19 | Fidelity Advisor® Health Care I | 450.00K (1.10%) | -90.00K Decreased by -20.00% | Nov 30, 23 |
| 20 | Fidelity® Small Cap Index | 447.78K (1.09%) | 12.05K Increased by +2.69% | Oct 31, 23 |