| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | venBio Select Advisor LLC | 10.30M (10.66%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | BlackRock Inc | 9.61M (9.94%) | 1.82M Increased by +18.92% | Dec 31, 23 |
| 3 | RA Capital Management, LLC | 6.94M (7.18%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 4 | HHG PLC | 6.80M (7.04%) | -943.10K Decreased by -13.86% | Sep 30, 23 |
| 5 | Vanguard Group Inc | 5.75M (5.95%) | 598.71K Increased by +10.42% | Sep 30, 23 |
| 6 | Adage Capital Partners Gp LLC | 4.13M (4.27%) | -276.29K Decreased by -6.70% | Sep 30, 23 |
| 7 | Perceptive Advisors LLC | 4.04M (4.18%) | 309.94K Increased by +7.67% | Sep 30, 23 |
| 8 | Cormorant Asset Management, LLC | 3.85M (3.98%) | 50.00K Increased by +1.30% | Sep 30, 23 |
| 9 | Jennison Associates LLC | 3.56M (3.68%) | 1.88M Increased by +52.98% | Sep 30, 23 |
| 10 | Franklin Resources Inc | 3.27M (3.38%) | -39.99K Decreased by -1.22% | Dec 31, 23 |
| 11 | Holocene Advisors, LP | 3.12M (3.23%) | 3.12M Increased by +100.00% | Sep 30, 23 |
| 12 | Octagon Capital Advisors LP | 3.07M (3.18%) | -1.50M Decreased by -48.71% | Sep 30, 23 |
| 13 | FMR Inc | 3.06M (3.17%) | 1.49M Increased by +48.76% | Dec 31, 23 |
| 14 | State Street Corporation | 2.80M (2.90%) | 511.97K Increased by +18.30% | Dec 31, 23 |
| 15 | Point72 Asset Management, L.P. | 2.43M (2.51%) | 2.43M Increased by +100.00% | Sep 30, 23 |
| 16 | Geode Capital Management, LLC | 2.38M (2.46%) | 304.55K Increased by +12.80% | Dec 31, 23 |
| 17 | Fred Alger Management, LLC | 2.17M (2.25%) | 2.17M Increased by +100.00% | Sep 30, 23 |
| 18 | T. Rowe Price Associates, Inc. | 1.90M (1.97%) | 1.81M Increased by +95.04% | Sep 30, 23 |
| 19 | Wagonhound Investments, LP | 1.84M (1.90%) | 1.14M Increased by +62.12% | Sep 30, 23 |
| 20 | Foresite Capital Management IV, LLC | 1.79M (1.85%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.47M (3.59%) | 5.66K Increased by +0.16% | Nov 30, 23 |
| 2 | iShares Russell 2000 ETF | 3.01M (3.12%) | 19.18K Increased by +0.64% | Dec 29, 23 |
| 3 | Franklin Biotechnology Discv A(acc)USD | 1.68M (1.73%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 4 | Janus Henderson Global Life Sciences | 1.67M (1.73%) | 10.79K Increased by +0.64% | Sep 30, 23 |
| 5 | Janus Henderson Global Life Sciences D | 1.67M (1.73%) | 10.79K Increased by +0.64% | Sep 30, 23 |
| 6 | PGIM Jennison Health Sciences Z | 1.65M (1.70%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 7 | Alger Small Cap Focus Composite | 1.61M (1.67%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 8 | Alger Small Cap Focus I | 1.61M (1.67%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 1.50M (1.56%) | 11.43K Increased by +0.76% | Nov 30, 23 |
| 10 | Janus Selection Global Life Science AUSD | 1.29M (1.33%) | -27.02K Decreased by -2.10% | Sep 30, 23 |
| 11 | Janus Henderson Glb Life Scn I2 USD | 1.24M (1.29%) | -27.61K Decreased by -2.22% | Nov 30, 23 |
| 12 | Jennison Health Sciences Equity | 1.22M (1.26%) | -270.45K Decreased by -22.15% | Dec 31, 23 |
| 13 | Janus Henderson Triton D | 1.19M (1.24%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | Janus Henderson US SMID Cap Growth | 1.19M (1.24%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | MEDICAL BioHealth EUR Acc | 1.17M (1.21%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 16 | Fidelity Small Cap Index | 1.16M (1.20%) | 10.49K Increased by +0.91% | Feb 29, 24 |
| 17 | iShares Russell 2000 Growth ETF | 1.01M (1.04%) | 0.00 Increased by 0.00% | Dec 29, 23 |
| 18 | Fidelity® Small Cap Index | 945.09K (0.98%) | 25.66K Increased by +2.71% | Oct 31, 23 |
| 19 | iShares Biotechnology ETF | 806.36K (0.83%) | -735.00 Decreased by -0.09% | Dec 29, 23 |
| 20 | Fidelity® Small Cap Growth | 794.24K (0.82%) | 684.13K Increased by +86.14% | Oct 31, 23 |