| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 16.77M (9.61%) | 1.28M Increased by +7.62% | Sep 30, 23 |
| 2 | Vanguard Group Inc | 15.39M (8.82%) | 302.27K Increased by +1.96% | Sep 30, 23 |
| 3 | Baker Bros Advisors LP | 12.71M (7.28%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 4 | venBio Select Advisor LLC | 11.55M (6.62%) | -505.00K Decreased by -4.37% | Sep 30, 23 |
| 5 | State Street Corporation | 10.47M (6.00%) | -1.80M Decreased by -17.17% | Sep 30, 23 |
| 6 | BRAIDWELL LP | 5.36M (3.07%) | 2.57M Increased by +47.94% | Sep 30, 23 |
| 7 | Millennium Management LLC | 4.98M (2.86%) | -318.81K Decreased by -6.40% | Sep 30, 23 |
| 8 | Pictet Asset Manangement SA | 4.19M (2.40%) | 4.19M Increased by +100.00% | Sep 30, 23 |
| 9 | Geode Capital Management, LLC | 3.91M (2.24%) | 78.52K Increased by +2.01% | Sep 30, 23 |
| 10 | RP Management, LLC | 3.85M (2.20%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 11 | Deerfield Management Co | 3.29M (1.88%) | 1.96M Increased by +59.77% | Sep 30, 23 |
| 12 | Fisher Asset Management, LLC | 3.19M (1.83%) | -1.14M Decreased by -35.77% | Sep 30, 23 |
| 13 | Kynam Capital Management, LP | 3.13M (1.80%) | 285.00K Increased by +9.10% | Sep 30, 23 |
| 14 | FMR Inc | 2.95M (1.69%) | 3.58K Increased by +0.12% | Sep 30, 23 |
| 15 | Point72 Asset Management, L.P. | 2.76M (1.58%) | -1.25M Decreased by -45.16% | Sep 30, 23 |
| 16 | Nuveen Asset Management, LLC | 2.57M (1.47%) | 1.58M Increased by +61.32% | Sep 30, 23 |
| 17 | GW&K Investment Management, LLC | 2.57M (1.47%) | -27.38K Decreased by -1.06% | Sep 30, 23 |
| 18 | Rock Springs Capital Management LP | 2.55M (1.46%) | 54.03K Increased by +2.12% | Sep 30, 23 |
| 19 | Eversept Partners, LLC | 2.48M (1.42%) | 106.99K Increased by +4.32% | Sep 30, 23 |
| 20 | Prosight Management, LP | 2.41M (1.38%) | -91.86K Decreased by -3.81% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BioPharma Credit Ord | 17.26M (9.89%) | 17.26M Increased by +100.00% | Jun 30, 23 |
| 2 | SPDR® S&P Biotech ETF | 8.48M (4.86%) | -49.10K Decreased by -0.58% | Dec 31, 23 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 5.94M (3.41%) | 15.58K Increased by +0.26% | Nov 30, 23 |
| 4 | iShares Russell 2000 ETF | 5.06M (2.90%) | 32.21K Increased by +0.64% | Dec 29, 23 |
| 5 | Pictet-Biotech P USD | 2.81M (1.61%) | 9.49K Increased by +0.34% | Jun 30, 23 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 2.70M (1.55%) | 23.37K Increased by +0.86% | Nov 30, 23 |
| 7 | Fidelity® Select Biotechnology | 2.58M (1.48%) | -225.50K Decreased by -8.74% | Nov 30, 23 |
| 8 | Vanguard Small Cap Index | 2.44M (1.40%) | 7.62K Increased by +0.31% | Nov 30, 23 |
| 9 | Eventide Healthcare & Life Sciences I | 1.97M (1.13%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 10 | Fidelity® Small Cap Index | 1.82M (1.05%) | 49.54K Increased by +2.71% | Oct 31, 23 |
| 11 | Pictet-Global Megatrend Sel I USD | 1.75M (1.00%) | -6.90K Decreased by -0.39% | Jun 30, 23 |
| 12 | iShares Biotechnology ETF | 1.49M (0.85%) | -1.36K Decreased by -0.09% | Dec 29, 23 |
| 13 | Vanguard Small Cap Growth Index Inv | 1.37M (0.78%) | 6.97K Increased by +0.51% | Nov 30, 23 |
| 14 | BNP Paribas Health Cr Innovtr Cl Cap | 1.28M (0.73%) | -120.93K Decreased by -9.45% | Nov 30, 23 |
| 15 | iShares Russell 2000 Growth ETF | 1.27M (0.73%) | 0.00 Increased by 0.00% | Dec 29, 23 |
| 16 | CREF Stock R1 | 1.22M (0.70%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 17 | State St Russell Sm/Mid Cp® Indx NL Cl C | 1.13M (0.64%) | 71.00K Increased by +6.31% | Dec 31, 23 |
| 18 | Fidelity® Extended Market Index | 1.05M (0.60%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 19 | Direxion Daily S&P Biotech Bull 3X ETF | 1.02M (0.58%) | 37.24K Increased by +3.66% | Dec 28, 23 |
| 20 | Schwab US Small-Cap ETF™ | 931.64K (0.53%) | 417.00 Increased by +0.04% | Dec 30, 23 |