| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | EcoR1 Capital, LLC | 5.47M (11.05%) | 1.45M Increased by +26.51% | Sep 30, 23 |
| 2 | BlackRock Inc | 4.97M (10.04%) | 66.14K Increased by +1.33% | Sep 30, 23 |
| 3 | FMR Inc | 4.87M (9.84%) | 466.67K Increased by +9.59% | Sep 30, 23 |
| 4 | Vanguard Group Inc | 4.61M (9.31%) | 90.43K Increased by +1.96% | Sep 30, 23 |
| 5 | T. Rowe Price Associates, Inc. | 2.69M (5.43%) | -5.37K Decreased by -0.20% | Sep 30, 23 |
| 6 | Avidity Partners Management LP | 2.61M (5.28%) | -158.23K Decreased by -6.05% | Sep 30, 23 |
| 7 | Bellevue Group AG | 2.13M (4.29%) | -1.80K Decreased by -0.08% | Sep 30, 23 |
| 8 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 2.09M (4.22%) | 285.01K Increased by +13.65% | Sep 30, 23 |
| 9 | JPMorgan Chase & Co | 1.99M (4.02%) | -8.98K Decreased by -0.45% | Sep 30, 23 |
| 10 | New Leaf Venture Partners, L.L.C. | 1.29M (2.61%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 11 | State Street Corporation | 1.16M (2.34%) | 42.61K Increased by +3.67% | Sep 30, 23 |
| 12 | Geode Capital Management, LLC | 1.06M (2.14%) | 62.42K Increased by +5.90% | Sep 30, 23 |
| 13 | Millennium Management LLC | 828.13K (1.67%) | 421.97K Increased by +50.95% | Sep 30, 23 |
| 14 | American Century Companies Inc | 813.47K (1.64%) | -46.51K Decreased by -5.72% | Sep 30, 23 |
| 15 | Citadel Advisors Llc | 624.58K (1.26%) | -265.02K Decreased by -42.43% | Sep 30, 23 |
| 16 | Finepoint Capital LP | 504.70K (1.02%) | 93.20K Increased by +18.47% | Sep 30, 23 |
| 17 | Aquilo Capital Management, LLC | 489.15K (0.99%) | -134.79K Decreased by -27.56% | Sep 30, 23 |
| 18 | Northern Trust Corp | 477.60K (0.97%) | 14.91K Increased by +3.12% | Sep 30, 23 |
| 19 | Dimensional Fund Advisors, Inc. | 469.40K (0.95%) | 256.69K Increased by +54.68% | Sep 30, 23 |
| 20 | Candriam Luxembourg S.C.A. | 447.55K (0.90%) | -20.00K Decreased by -4.47% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 2.12M (4.28%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.42M (2.87%) | 215.00 Increased by +0.02% | Nov 30, 23 |
| 3 | iShares Russell 2000 ETF | 1.31M (2.65%) | 8.34K Increased by +0.64% | Dec 29, 23 |
| 4 | US Small-Cap Growth II Equity Comp | 1.25M (2.52%) | 1.25M Increased by +100.00% | Jun 30, 23 |
| 5 | T. Rowe Price New Horizons | 1.25M (2.52%) | -428.00 Decreased by -0.03% | Sep 30, 23 |
| 6 | Vanguard Small Cap Index | 1.18M (2.38%) | 3.62K Increased by +0.31% | Nov 30, 23 |
| 7 | FIAM Small Cap Core CIT Cl B | 995.70K (2.01%) | 10.70K Increased by +1.07% | Oct 31, 23 |
| 8 | FIAM Small Cap Core Composite | 985.00K (1.99%) | 521.00K Increased by +52.89% | Sep 30, 23 |
| 9 | JPM Global Healthcare C (acc) USD | 902.23K (1.82%) | 321.49K Increased by +35.63% | Nov 30, 23 |
| 10 | Vanguard Explorer Inv | 819.77K (1.66%) | 116.81K Increased by +14.25% | Sep 30, 23 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 781.63K (1.58%) | 1.46K Increased by +0.19% | Nov 30, 23 |
| 12 | JPMorgan Small Cap Growth A | 692.25K (1.40%) | 3.46K Increased by +0.50% | Nov 30, 23 |
| 13 | Vanguard Small Cap Growth Index Inv | 656.89K (1.33%) | 3.35K Increased by +0.51% | Nov 30, 23 |
| 14 | T. Rowe Price Health Sciences | 484.00K (0.98%) | -13.74K Decreased by -2.84% | Sep 30, 23 |
| 15 | Fidelity® Small Cap Index | 474.69K (0.96%) | 13.34K Increased by +2.81% | Oct 31, 23 |
| 16 | iShares Russell 2000 Growth ETF | 411.27K (0.83%) | 0.00 Increased by 0.00% | Dec 29, 23 |
| 17 | Fidelity® Small Cap Growth | 396.92K (0.80%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 18 | Belfius Equities Cure C Cap | 368.25K (0.74%) | 70.00K Increased by +19.01% | Nov 30, 23 |
| 19 | iShares Biotechnology ETF | 353.09K (0.71%) | -322.00 Decreased by -0.09% | Dec 29, 23 |
| 20 | Nomura ACI AdvMed Impact Inv MF | 352.30K (0.71%) | 28.89K Increased by +8.20% | Jun 19, 23 |