| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 4.69M (11.74%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | Orbimed Advisors, LLC | 4.08M (10.21%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 3 | Great Point Partners LLC | 3.08M (7.70%) | -285.06K Decreased by -9.26% | Sep 30, 23 |
| 4 | Paradigm Biocapital Advisors LP | 2.42M (6.06%) | -2.22K Decreased by -0.09% | Sep 30, 23 |
| 5 | BlackRock Inc | 2.35M (5.89%) | 70.22K Increased by +2.99% | Sep 30, 23 |
| 6 | Cormorant Asset Management, LLC | 1.90M (4.75%) | 1.90M Increased by +100.00% | Sep 30, 23 |
| 7 | Vanguard Group Inc | 1.47M (3.69%) | 70.91K Increased by +4.81% | Sep 30, 23 |
| 8 | T. Rowe Price Associates, Inc. | 1.40M (3.49%) | 1.37M Increased by +98.44% | Sep 30, 23 |
| 9 | COMMODORE CAPITAL LP | 1.32M (3.32%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 10 | Artal Group S A | 1.19M (2.99%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 11 | Woodline Partners LP | 1.04M (2.60%) | 801.21K Increased by +77.13% | Sep 30, 23 |
| 12 | Vivo Capital, LLC | 914.91K (2.29%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | Octagon Capital Advisors LP | 750.00K (1.88%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | Ghost Tree Capital, LLC | 664.13K (1.66%) | 316.70K Increased by +47.69% | Sep 30, 23 |
| 15 | Avidity Partners Management LP | 657.28K (1.64%) | -401.22K Decreased by -61.04% | Sep 30, 23 |
| 16 | Geode Capital Management, LLC | 628.92K (1.57%) | 10.95K Increased by +1.74% | Sep 30, 23 |
| 17 | State Street Corporation | 605.54K (1.52%) | 32.70K Increased by +5.40% | Sep 30, 23 |
| 18 | FMR Inc | 464.81K (1.16%) | -210.77K Decreased by -45.35% | Sep 30, 23 |
| 19 | Tri Locum Partners LP | 314.03K (0.79%) | -17.96K Decreased by -5.72% | Sep 30, 23 |
| 20 | Renaissance Technologies Corp | 288.19K (0.72%) | -31.10K Decreased by -10.79% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.27M (3.18%) | 401.00K Increased by +31.54% | Nov 30, 23 |
| 2 | iShares Russell 2000 ETF | 874.52K (2.19%) | 5.55K Increased by +0.63% | Dec 29, 23 |
| 3 | T. Rowe Price New Horizons | 868.02K (2.17%) | 868.02K Increased by +100.00% | Sep 30, 23 |
| 4 | SPDR® S&P Biotech ETF | 711.07K (1.78%) | -4.12K Decreased by -0.58% | Dec 31, 23 |
| 5 | Franklin Biotechnology Discv A(acc)USD | 703.70K (1.76%) | 261.00K Increased by +37.09% | Nov 30, 23 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 543.24K (1.36%) | 154.28K Increased by +28.40% | Nov 30, 23 |
| 7 | Candriam Eqs L Biotech C USD Cap | 480.00K (1.20%) | 480.00K Increased by +100.00% | Nov 30, 23 |
| 8 | Franklin Biotechnology Discovery A | 324.80K (0.81%) | 121.42K Increased by +37.38% | Nov 30, 23 |
| 9 | Fidelity® Small Cap Index | 308.42K (0.77%) | 9.00K Increased by +2.92% | Oct 31, 23 |
| 10 | iShares Biotechnology ETF | 275.49K (0.69%) | -251.00 Decreased by -0.09% | Dec 29, 23 |
| 11 | Fidelity® Select Biotechnology | 220.80K (0.55%) | 98.70K Increased by +44.70% | Nov 30, 23 |
| 12 | Invesco Dorsey Wright SmallCap Momt ETF | 209.69K (0.52%) | 1.39K Increased by +0.66% | Dec 29, 23 |
| 13 | State St Russell Sm/Mid Cp® Indx NL Cl C | 192.50K (0.48%) | 11.40K Increased by +5.92% | Dec 31, 23 |
| 14 | Schwab US Small-Cap ETF™ | 179.15K (0.45%) | 78.00 Increased by +0.04% | Dec 30, 23 |
| 15 | Fidelity® Extended Market Index | 157.28K (0.39%) | 4.48K Increased by +2.85% | Nov 30, 23 |
| 16 | iShares Russell 2000 Growth ETF | 153.96K (0.39%) | 0.00 Increased by 0.00% | Dec 29, 23 |
| 17 | T. Rowe Price New Horizons Tr-Z | 143.82K (0.36%) | 143.82K Increased by +100.00% | Sep 30, 23 |
| 18 | iShares Russell 2000 Value ETF | 143.77K (0.36%) | 267.00 Increased by +0.19% | Dec 29, 23 |
| 19 | State St Russell Sm Cap® Indx SL Cl I | 120.44K (0.30%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 20 | Xtrackers S&P 500 Swap ETF 1C | 112.43K (0.28%) | 0.00 Increased by 0.00% | Nov 30, 23 |