| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 42.86M (39.32%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | Vanguard Group Inc | 13.62M (12.49%) | -238.11K Decreased by -1.75% | Sep 30, 23 |
| 3 | RTW INVESTMENTS, LLC | 11.58M (10.62%) | 1.79M Increased by +15.49% | Sep 30, 23 |
| 4 | BlackRock Inc | 10.03M (9.20%) | -10.92K Decreased by -0.11% | Sep 30, 23 |
| 5 | EcoR1 Capital, LLC | 5.99M (5.50%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 6 | FMR Inc | 5.30M (4.86%) | -19.26K Decreased by -0.36% | Sep 30, 23 |
| 7 | T. Rowe Price Associates, Inc. | 5.23M (4.80%) | -783.75K Decreased by -14.99% | Sep 30, 23 |
| 8 | State Street Corporation | 5.21M (4.78%) | -206.59K Decreased by -3.96% | Sep 30, 23 |
| 9 | D. E. Shaw & Co LP | 4.79M (4.39%) | -474.08K Decreased by -9.90% | Sep 30, 23 |
| 10 | Fred Alger Management, LLC | 3.11M (2.85%) | 867.82K Increased by +27.91% | Sep 30, 23 |
| 11 | Geode Capital Management, LLC | 2.58M (2.37%) | 84.04K Increased by +3.26% | Sep 30, 23 |
| 12 | Millennium Management LLC | 2.41M (2.21%) | 1.93M Increased by +79.79% | Sep 30, 23 |
| 13 | Palo Alto Investors, LLC | 2.41M (2.21%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | Morgan Stanley - Brokerage Accounts | 1.86M (1.70%) | -1.87M Decreased by -100.82% | Sep 30, 23 |
| 15 | Emerald Advisers, LLC | 1.68M (1.54%) | 64.10K Increased by +3.81% | Sep 30, 23 |
| 16 | First Trust Advisors L.P. | 1.63M (1.49%) | -875.66K Decreased by -53.76% | Sep 30, 23 |
| 17 | Jacobs Levy Equity Management, Inc. | 1.42M (1.31%) | -411.62K Decreased by -28.90% | Sep 30, 23 |
| 18 | Pictet Asset Manangement SA | 1.35M (1.24%) | 1.35M Increased by +100.00% | Sep 30, 23 |
| 19 | Emerald Mutual Fund Advisers Trust | 1.30M (1.20%) | 12.89K Increased by +0.99% | Sep 30, 23 |
| 20 | Jupiter Asset Management Limited | 1.28M (1.17%) | 4.93K Increased by +0.39% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.84M (3.53%) | 6.08K Increased by +0.16% | Nov 30, 23 |
| 2 | SPDR® S&P Biotech ETF | 3.80M (3.48%) | -22.00K Decreased by -0.58% | Dec 31, 23 |
| 3 | iShares Russell 2000 ETF | 3.24M (2.97%) | 20.60K Increased by +0.64% | Dec 29, 23 |
| 4 | Vanguard Small Cap Index | 3.18M (2.92%) | 9.73K Increased by +0.31% | Nov 30, 23 |
| 5 | Fidelity Growth Compy Commingled Pl O | 2.47M (2.27%) | 12.26K Increased by +0.50% | Nov 30, 23 |
| 6 | US Small-Cap Growth II Equity Comp | 1.80M (1.65%) | 1.80M Increased by +100.00% | Jun 30, 23 |
| 7 | Vanguard Small Cap Growth Index Inv | 1.78M (1.63%) | 9.04K Increased by +0.51% | Nov 30, 23 |
| 8 | T. Rowe Price New Horizons | 1.71M (1.57%) | -92.71K Decreased by -5.42% | Sep 30, 23 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 1.70M (1.56%) | 2.91K Increased by +0.17% | Nov 30, 23 |
| 10 | First Trust NYSE Arca Biotech ETF | 1.70M (1.56%) | -139.00 Decreased by -0.01% | Dec 28, 23 |
| 11 | Fidelity® Growth Company | 1.70M (1.56%) | 57.80K Increased by +3.41% | Nov 30, 23 |
| 12 | T. Rowe Price Health Sciences | 1.26M (1.16%) | -743.82K Decreased by -58.84% | Sep 30, 23 |
| 13 | iShares Biotechnology ETF | 1.22M (1.12%) | -1.11K Decreased by -0.09% | Dec 29, 23 |
| 14 | Fidelity® Small Cap Index | 1.17M (1.07%) | 31.83K Increased by +2.73% | Oct 31, 23 |
| 15 | iShares Russell 2000 Growth ETF | 1.07M (0.98%) | 0.00 Increased by 0.00% | Dec 29, 23 |
| 16 | Alger Weatherbie Specialized Growth A | 1.00M (0.92%) | 899.00 Increased by +0.09% | Oct 31, 23 |
| 17 | T. Rowe Price Integrated US Sm Gr Eq | 981.31K (0.90%) | 195.50K Increased by +19.92% | Sep 30, 23 |
| 18 | TRP Integrated US Small-Cap Gr Eq | 981.31K (0.90%) | 195.50K Increased by +19.92% | Sep 30, 23 |
| 19 | Fidelity® Growth Company K6 | 713.90K (0.65%) | -60.00K Decreased by -8.40% | Oct 31, 23 |
| 20 | State St Russell Sm/Mid Cp® Indx NL Cl C | 708.15K (0.65%) | 26.70K Increased by +3.77% | Dec 31, 23 |